null
SMILES: N[C@@H](Cc1ccc(cc1)-c1nc(N)nc(NC(c2ccc3ccccc3c2)C(F)(F)F)n1)C(O)=O
InChI Key: InChIKey=PBPZTYJTIDVGLQ-OYKVQYDMSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tryptophan 5-hydroxylase 1 (Homo sapiens (Human)) | BDBM50300939 ((2S)-2-amino-3-(4-(4-amino-6-(2,2,2-trifluoro-1-(n...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Princ Curated by ChEMBL | Assay Description Inhibition of human recombinant TPH1 by continuous fluorescence assay | Bioorg Med Chem Lett 19: 5229-32 (2009) Article DOI: 10.1016/j.bmcl.2009.07.005 BindingDB Entry DOI: 10.7270/Q2MS3SV0 | |||||||||||
More data for this Ligand-Target Pair |