BDBM50306438 11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexahydro-5H-benzo[d]naphtho[2,1-b]azepine-4-carbaldehyde O-methyl oxime::CHEMBL599134

SMILES: CO\N=C\c1cccc2[C@H]3[C@H](CCc12)N(C)CCc1cc(Cl)c(O)cc31

InChI Key: InChIKey=XSNJPPIVERUUQP-OMJZWIOZSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50306438   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50306438 (11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...) Show SMILES CO\N=C\c1cccc2[C@H]3[C@H](CCc12)N(C)CCc1cc(Cl)c(O)cc31 |r| Show InChI InChI=1S/C21H23ClN2O2/c1-24-9-8-13-10-18(22)20(25)11-17(13)21-16-5-3-4-14(12-23-26-2)15(16)6-7-19(21)24/h3-5,10-12,19,21,25H,6-9H2,1-2H3/b23-12+/t19-,21+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]SCh23390 from dopamine D1 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50306438 (11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...) Show SMILES CO\N=C\c1cccc2[C@H]3[C@H](CCc12)N(C)CCc1cc(Cl)c(O)cc31 |r| Show InChI InChI=1S/C21H23ClN2O2/c1-24-9-8-13-10-18(22)20(25)11-17(13)21-16-5-3-4-14(12-23-26-2)15(16)6-7-19(21)24/h3-5,10-12,19,21,25H,6-9H2,1-2H3/b23-12+/t19-,21+/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand from dopamine D5 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50306438 (11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...) Show SMILES CO\N=C\c1cccc2[C@H]3[C@H](CCc12)N(C)CCc1cc(Cl)c(O)cc31 |r| Show InChI InChI=1S/C21H23ClN2O2/c1-24-9-8-13-10-18(22)20(25)11-17(13)21-16-5-3-4-14(12-23-26-2)15(16)6-7-19(21)24/h3-5,10-12,19,21,25H,6-9H2,1-2H3/b23-12+/t19-,21+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	483	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]methylspiperon from dopamine D2 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50306438 (11-chloro-12-hydroxy-7-methyl-6,6a,7,8,9,13b-hexah...) Show SMILES CO\N=C\c1cccc2[C@H]3[C@H](CCc12)N(C)CCc1cc(Cl)c(O)cc31 |r| Show InChI InChI=1S/C21H23ClN2O2/c1-24-9-8-13-10-18(22)20(25)11-17(13)21-16-5-3-4-14(12-23-26-2)15(16)6-7-19(21)24/h3-5,10-12,19,21,25H,6-9H2,1-2H3/b23-12+/t19-,21+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand from dopamine D4 receptor expressed in mouse LTK cells by scintillation counting				Bioorg Med Chem Lett 20: 832-5 (2010) Article DOI: 10.1016/j.bmcl.2009.12.094 BindingDB Entry DOI: 10.7270/Q2FX79JH
					More data for this Ligand-Target Pair