null
SMILES: COc1cc2nccc(Oc3ccc(NC(=O)C4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC
InChI Key: InChIKey=GFMJATLKGABDIJ-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50383209 (CHEMBL2032033) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant c-met-mediated gastrin phosphorylation by HTRF assay | J Med Chem 55: 1858-67 (2012) Article DOI: 10.1021/jm201330u BindingDB Entry DOI: 10.7270/Q2ZK5HQP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Hepatocyte growth factor receptor (Homo sapiens (Human)) | BDBM50383209 (CHEMBL2032033) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 123 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc. Curated by ChEMBL | Assay Description Inhibition of HGF-mediated c-met autophosphorylation in serum-starved human PC3 cells after 1 hr by electrochemiluminescent immunoassay | J Med Chem 55: 1858-67 (2012) Article DOI: 10.1021/jm201330u BindingDB Entry DOI: 10.7270/Q2ZK5HQP | |||||||||||
More data for this Ligand-Target Pair |