BDBM50383343 CHEMBL2029805
SMILES: CC(C)CCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2)c(C#N)c1=O
InChI Key: InChIKey=GAXYDHPYPPPJHR-UHFFFAOYSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Metabotropic glutamate receptor 2 (Homo sapiens (Human)) | BDBM50383343 (CHEMBL2029805) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 447 | n/a | n/a | n/a | n/a |
Janssen-Cilag S.A. Curated by ChEMBL | Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l... | J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020 | |||||||||||
More data for this Ligand-Target Pair |