BDBM50383343 CHEMBL2029805

SMILES: CC(C)CCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2)c(C#N)c1=O

InChI Key: InChIKey=GAXYDHPYPPPJHR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50383343   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50383343 (CHEMBL2029805) Show SMILES CC(C)CCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2)c(C#N)c1=O Show InChI InChI=1S/C23H23N3O2/c1-16(2)9-12-26-13-10-21(22(15-24)23(26)27)18-4-6-19(7-5-18)28-20-8-11-25-17(3)14-20/h4-8,10-11,13-14,16H,9,12H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	447	n/a	n/a	n/a	n/a
Janssen-Cilag S.A. Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGlu2 receptor expressed in CHO cells assessed as glutamate-induced [35S]GTPgammaS binding after 30 mins by l...				J Med Chem 55: 2388-405 (2012) Article DOI: 10.1021/jm2016864 BindingDB Entry DOI: 10.7270/Q22B9020
					More data for this Ligand-Target Pair