null

SMILES: COc1ccc(CNc2cnc(N)nc2N)cc1

InChI Key: InChIKey=AUACRCYTCOSLMP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50391246   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydrofolate reductase (Candida albicans)	BDBM50391246 (CHEMBL369237) Show SMILES COc1ccc(CNc2cnc(N)nc2N)cc1 Show InChI InChI=1S/C12H15N5O/c1-18-9-4-2-8(3-5-9)6-15-10-7-16-12(14)17-11(10)13/h2-5,7,15H,6H2,1H3,(H4,13,14,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Leibniz Center for Medicine and Biosciences Curated by ChEMBL					Assay Description Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Escherichia coli				J Med Chem 47: 240-53 (2003) Article DOI: 10.1021/jm030931w BindingDB Entry DOI: 10.7270/Q2DB831H
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Rattus norvegicus (rat))	BDBM50391246 (CHEMBL369237) Show SMILES COc1ccc(CNc2cnc(N)nc2N)cc1 Show InChI InChI=1S/C12H15N5O/c1-18-9-4-2-8(3-5-9)6-15-10-7-16-12(14)17-11(10)13/h2-5,7,15H,6H2,1H3,(H4,13,14,16,17)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a
Leibniz Center for Medicine and Biosciences Curated by ChEMBL					Assay Description Inhibitory activity against cell free dihydrofolate reductase (DHFR) from rat				J Med Chem 47: 240-53 (2003) Article DOI: 10.1021/jm030931w BindingDB Entry DOI: 10.7270/Q2DB831H
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Candida albicans)	BDBM50391246 (CHEMBL369237) Show SMILES COc1ccc(CNc2cnc(N)nc2N)cc1 Show InChI InChI=1S/C12H15N5O/c1-18-9-4-2-8(3-5-9)6-15-10-7-16-12(14)17-11(10)13/h2-5,7,15H,6H2,1H3,(H4,13,14,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leibniz Center for Medicine and Biosciences Curated by ChEMBL					Assay Description Inhibitory activity against cell free dihydrofolate redutase (DHFR) from Mycobacterium lufu				J Med Chem 47: 240-53 (2003) Article DOI: 10.1021/jm030931w BindingDB Entry DOI: 10.7270/Q2DB831H
					More data for this Ligand-Target Pair
Dihydrofolate reductase (Candida albicans)	BDBM50391246 (CHEMBL369237) Show SMILES COc1ccc(CNc2cnc(N)nc2N)cc1 Show InChI InChI=1S/C12H15N5O/c1-18-9-4-2-8(3-5-9)6-15-10-7-16-12(14)17-11(10)13/h2-5,7,15H,6H2,1H3,(H4,13,14,16,17)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Leibniz Center for Medicine and Biosciences Curated by ChEMBL					Assay Description Inhibitory activity against cell free dihydrofolate reductase (DHFR) from Candida albicans				J Med Chem 47: 240-53 (2003) Article DOI: 10.1021/jm030931w BindingDB Entry DOI: 10.7270/Q2DB831H
					More data for this Ligand-Target Pair