BDBM50403160 CHEMBL4169649

SMILES: Cl.Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)CCCCN)c1

InChI Key: InChIKey=PMNBEGAALHKAJN-MHWRWJLKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50403160   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50403160 (CHEMBL4169649) Show SMILES Cl.Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)CCCCN)c1 |r| Show InChI InChI=1S/C18H28O6P2/c1-15(2)6-4-7-16(3)10-17-8-5-9-18(11-17)12-24-13-25(19,20)14-26(21,22)23/h5-6,8-11H,4,7,12-14H2,1-3H3,(H,19,20)(H2,21,22,23)/b16-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of recombinant mouse iNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in ...				Eur J Med Chem 152: 53-64 (2018) Article DOI: 10.1016/j.ejmech.2018.04.027 BindingDB Entry DOI: 10.7270/Q2C2500M
					More data for this Ligand-Target Pair
Nitric-oxide synthase, endothelial (Bos taurus (bovine))	BDBM50403160 (CHEMBL4169649) Show SMILES Cl.Cl.Cl.CC(=N)NCc1cccc(CNC(=O)[C@@H](N)CCCCN)c1 |r| Show InChI InChI=1S/C18H28O6P2/c1-15(2)6-4-7-16(3)10-17-8-5-9-18(11-17)12-24-13-25(19,20)14-26(21,22)23/h5-6,8-11H,4,7,12-14H2,1-3H3,(H,19,20)(H2,21,22,23)/b16-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.11E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Chieti "G. d'Annunzio" Curated by ChEMBL					Assay Description Inhibition of recombinant bovine eNOS using [3H]L-arginine as substrate preincubated for 15 mins followed by NADPH addition measured after 20 mins in...				Eur J Med Chem 152: 53-64 (2018) Article DOI: 10.1016/j.ejmech.2018.04.027 BindingDB Entry DOI: 10.7270/Q2C2500M
					More data for this Ligand-Target Pair