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SMILES: NOC(=O)c1nnn(CCNS(=O)(=O)c2ccccc2)c1C(=O)ON

InChI Key: InChIKey=CODQJCWISVUNOM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424315   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E synthase


(Homo sapiens (Human))		BDBM50424315
PNG
(CHEMBL2314491)
Show SMILES NOC(=O)c1nnn(CCNS(=O)(=O)c2ccccc2)c1C(=O)ON
Show InChI InChI=1S/C12H14N6O6S/c13-23-11(19)9-10(12(20)24-14)18(17-16-9)7-6-15-25(21,22)8-4-2-1-3-5-8/h1-5,15H,6-7,13-14H2
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Article
PubMed
n/an/a 2.33E+4n/an/an/an/an/an/a



Kyung Hee University

Curated by ChEMBL


Assay Description
Inhibition of mPGES1 (unknown origin) using PGH2 as substrate incubated for 30 mins prior to substrate addition by PGH2-coupled spectrophotometric an...

Bioorg Med Chem Lett 23: 75-80 (2012)


Article DOI: 10.1016/j.bmcl.2012.11.019
BindingDB Entry DOI: 10.7270/Q2DB8359
More data for this
Ligand-Target Pair