Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Prostaglandin E synthase' and Ligand = 'BDBM50424315'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50424315 (CHEMBL2314491) Show SMILES NOC(=O)c1nnn(CCNS(=O)(=O)c2ccccc2)c1C(=O)ON Show InChI InChI=1S/C12H14N6O6S/c13-23-11(19)9-10(12(20)24-14)18(17-16-9)7-6-15-25(21,22)8-4-2-1-3-5-8/h1-5,15H,6-7,13-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Kyung Hee University Curated by ChEMBL					Assay Description Inhibition of mPGES1 (unknown origin) using PGH2 as substrate incubated for 30 mins prior to substrate addition by PGH2-coupled spectrophotometric an...				Bioorg Med Chem Lett 23: 75-80 (2012) Article DOI: 10.1016/j.bmcl.2012.11.019 BindingDB Entry DOI: 10.7270/Q2DB8359
					More data for this Ligand-Target Pair