null

SMILES: COc1ccc2nccc(\C=C\[C@@H]3CC[C@H](CO3)NCc3cc4OCCOc4cn3)c2n1

InChI Key: InChIKey=ROYGGNJCSVBHRS-ULIAPGIUSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440314   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus)	BDBM50440314 (CHEMBL2424882) Show SMILES COc1ccc2nccc(\C=C\[C@@H]3CC[C@H](CO3)NCc3cc4OCCOc4cn3)c2n1 |r| Show InChI InChI=1S/C24H26N4O4/c1-29-23-7-6-20-24(28-23)16(8-9-25-20)2-4-19-5-3-17(15-32-19)26-13-18-12-21-22(14-27-18)31-11-10-30-21/h2,4,6-9,12,14,17,19,26H,3,5,10-11,13,15H2,1H3/b4-2+/t17-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of wild type Staphylococcus aureus ATCC 29213 topoisomerase-4 subunit 2GrlA/2GrlB assessed as pBR322 relaxation after 1 hr				J Med Chem 56: 7396-415 (2013) Article DOI: 10.1021/jm400963y BindingDB Entry DOI: 10.7270/Q2HT2QRV
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM50440314 (CHEMBL2424882) Show SMILES COc1ccc2nccc(\C=C\[C@@H]3CC[C@H](CO3)NCc3cc4OCCOc4cn3)c2n1 |r| Show InChI InChI=1S/C24H26N4O4/c1-29-23-7-6-20-24(28-23)16(8-9-25-20)2-4-19-5-3-17(15-32-19)26-13-18-12-21-22(14-27-18)31-11-10-30-21/h2,4,6-9,12,14,17,19,26H,3,5,10-11,13,15H2,1H3/b4-2+/t17-,19-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
Actelion Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of wild type Staphylococcus aureus DNA gyrase subunit 2GyrA/2GyrB assessed as pBR322 supercoiling after 1 hr				J Med Chem 56: 7396-415 (2013) Article DOI: 10.1021/jm400963y BindingDB Entry DOI: 10.7270/Q2HT2QRV
					More data for this Ligand-Target Pair