BDBM50461412 CHEMBL4228054
SMILES: CCCCCN1CCC(C1)c1cccc(O)c1
InChI Key: InChIKey=UXQSBUSPGKCLJW-UHFFFAOYSA-N
Data: 6 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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D(3) dopamine receptor (Homo sapiens (Human)) | BDBM50461412 (CHEMBL4228054) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 131 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Illinois University Edwardsville Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D3 receptor expressed in HEK293T cell membranes by radioligand binding assay | Bioorg Med Chem Lett 28: 1897-1902 (2018) Article DOI: 10.1016/j.bmcl.2018.03.084 BindingDB Entry DOI: 10.7270/Q2F47RS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM50461412 (CHEMBL4228054) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 164 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Illinois University Edwardsville Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D4 receptor expressed in stable HEK cell membranes by radioligand binding assay | Bioorg Med Chem Lett 28: 1897-1902 (2018) Article DOI: 10.1016/j.bmcl.2018.03.084 BindingDB Entry DOI: 10.7270/Q2F47RS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50461412 (CHEMBL4228054) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 326 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Illinois University Edwardsville Curated by ChEMBL | Assay Description Displacement of [3H]-Way100635 from 5HT1A receptor (unknown origin) expressed in stable CHO cell membranes by radioligand binding assay | Bioorg Med Chem Lett 28: 1897-1902 (2018) Article DOI: 10.1016/j.bmcl.2018.03.084 BindingDB Entry DOI: 10.7270/Q2F47RS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1A) dopamine receptor (Homo sapiens (Human)) | BDBM50461412 (CHEMBL4228054) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 542 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Illinois University Edwardsville Curated by ChEMBL | Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor expressed in HEK293T cell membranes by radioligand binding assay | Bioorg Med Chem Lett 28: 1897-1902 (2018) Article DOI: 10.1016/j.bmcl.2018.03.084 BindingDB Entry DOI: 10.7270/Q2F47RS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(1B) dopamine receptor (Homo sapiens (Human)) | BDBM50461412 (CHEMBL4228054) | UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 605 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Illinois University Edwardsville Curated by ChEMBL | Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor expressed in HEK293T cell membranes by radioligand binding assay | Bioorg Med Chem Lett 28: 1897-1902 (2018) Article DOI: 10.1016/j.bmcl.2018.03.084 BindingDB Entry DOI: 10.7270/Q2F47RS3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50461412 (CHEMBL4228054) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Illinois University Edwardsville Curated by ChEMBL | Assay Description Displacement of [3H]N-methylspiperone from human dopamine D2 receptor expressed in stable fibroblasts membranes by radioligand binding assay | Bioorg Med Chem Lett 28: 1897-1902 (2018) Article DOI: 10.1016/j.bmcl.2018.03.084 BindingDB Entry DOI: 10.7270/Q2F47RS3 | |||||||||||
More data for this Ligand-Target Pair |