BDBM50466841 CHEMBL4284572

SMILES: Cl.NCC(Nc1nccc(n1)-c1n[nH]c2nc(NCCN3CCOCC3)ncc12)c1ccccc1

InChI Key: InChIKey=RKPDJCDQIFIYFH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50466841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM50466841 (CHEMBL4284572) Show SMILES Cl.NCC(Nc1nccc(n1)-c1n[nH]c2nc(NCCN3CCOCC3)ncc12)c1ccccc1 Show InChI InChI=1S/C23H28N10O.ClH/c24-14-19(16-4-2-1-3-5-16)29-23-25-7-6-18(28-23)20-17-15-27-22(30-21(17)32-31-20)26-8-9-33-10-12-34-13-11-33;/h1-7,15,19H,8-14,24H2,(H,25,28,29)(H2,26,27,30,31,32);1H	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human full-length recombinant GST-tagged DYRK1B expressed in baculovirus expression system using RRRFRPASPLRGPPK as substrate after 60 ...				J Med Chem 61: 9791-9810 (2018) Article DOI: 10.1021/acs.jmedchem.8b00185 BindingDB Entry DOI: 10.7270/Q2H41V3Q
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50466841 (CHEMBL4284572) Show SMILES Cl.NCC(Nc1nccc(n1)-c1n[nH]c2nc(NCCN3CCOCC3)ncc12)c1ccccc1 Show InChI InChI=1S/C23H28N10O.ClH/c24-14-19(16-4-2-1-3-5-16)29-23-25-7-6-18(28-23)20-17-15-27-22(30-21(17)32-31-20)26-8-9-33-10-12-34-13-11-33;/h1-7,15,19H,8-14,24H2,(H,25,28,29)(H2,26,27,30,31,32);1H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human full-length GST-tagged DYRK1A expressed in baculovirus expression system using RRRFRPASPLRGPPK as substrate after 60 mins by TR-F...				J Med Chem 61: 9791-9810 (2018) Article DOI: 10.1021/acs.jmedchem.8b00185 BindingDB Entry DOI: 10.7270/Q2H41V3Q
					More data for this Ligand-Target Pair