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Found 1 hit Enz. Inhib. hit(s) with Target = 'Dual specificity tyrosine-phosphorylation-regulated kinase 1B' and Ligand = 'BDBM50466841'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dual specificity tyrosine-phosphorylation-regulated kinase 1B


(Homo sapiens (Human))		BDBM50466841
PNG
(CHEMBL4284572)
Show SMILES Cl.NCC(Nc1nccc(n1)-c1n[nH]c2nc(NCCN3CCOCC3)ncc12)c1ccccc1
Show InChI InChI=1S/C23H28N10O.ClH/c24-14-19(16-4-2-1-3-5-16)29-23-25-7-6-18(28-23)20-17-15-27-22(30-21(17)32-31-20)26-8-9-33-10-12-34-13-11-33;/h1-7,15,19H,8-14,24H2,(H,25,28,29)(H2,26,27,30,31,32);1H
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 18n/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human full-length recombinant GST-tagged DYRK1B expressed in baculovirus expression system using RRRFRPASPLRGPPK as substrate after 60 ...

J Med Chem 61: 9791-9810 (2018)


Article DOI: 10.1021/acs.jmedchem.8b00185
BindingDB Entry DOI: 10.7270/Q2H41V3Q
More data for this
Ligand-Target Pair