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SMILES: Cc1nccn1-c1cccc(OCCOc2ccc(cc2Cl)C#N)c1

InChI Key: InChIKey=WJVPADFVXZPWNZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50502486   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein-S-isoprenylcysteine O-methyltransferase


(Homo sapiens (Human))		BDBM50502486
PNG
(CHEMBL4468997)
Show SMILES Cc1nccn1-c1cccc(OCCOc2ccc(cc2Cl)C#N)c1
Show InChI InChI=1S/C19H16ClN3O2/c1-14-22-7-8-23(14)16-3-2-4-17(12-16)24-9-10-25-19-6-5-15(13-21)11-18(19)20/h2-8,11-12H,9-10H2,1H3
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.200n/an/an/an/an/an/a



Usona Institute

Curated by ChEMBL


Assay Description
Inhibition of recombinant human ICMT expressed in baculovirus infected Sf9 insect cells using SAM as substrate preincubated for 30 mins followed by s...

ACS Med Chem Lett 10: 1024-1025 (2019)


Article DOI: 10.1021/acsmedchemlett.9b00269
More data for this
Ligand-Target Pair