null

SMILES: COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1

InChI Key: InChIKey=OPMJBWVXRQIVBZ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50510569   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of ALK (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	375	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of RON (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	242	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRalpha (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	418	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of FLT1 (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	356	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50510569 (CHEMBL4533153) Show SMILES COc1cc2c(Oc3ccc(NC(=O)NS(=O)(=O)Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 Show InChI InChI=1S/C31H32F2N4O6S/c1-41-29-18-24-26(19-30(29)42-16-4-15-37-13-2-3-14-37)34-12-11-27(24)43-28-10-9-23(17-25(28)33)35-31(38)36-44(39,40)20-21-5-7-22(32)8-6-21/h5-12,17-19H,2-4,13-16,20H2,1H3,(H2,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
School of Marine Science and Technology Curated by ChEMBL					Assay Description Inhibition of KDR (unknown origin) using poly (Glu, Tyr) 4:1 substrate incubated for 30 mins by HTRF assay				Bioorg Med Chem 27: 2801-2812 (2019) Article DOI: 10.1016/j.bmc.2019.05.007
					More data for this Ligand-Target Pair