BDBM50516102 CHEMBL4457755

SMILES: COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2SC)cc1Cl

InChI Key: InChIKey=CZTLKMFTUWCPPK-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50516102 (CHEMBL4457755) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2SC)cc1Cl Show InChI InChI=1S/C19H22ClN3O2S/c1-25-16-6-5-14(12-15(16)20)22-19(24)13-7-10-23(11-8-13)18-17(26-2)4-3-9-21-18/h3-6,9,12-13H,7-8,10-11H2,1-2H3,(H,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743
					More data for this Ligand-Target Pair