Compile Data Set for Download or QSAR

Found 1777 hits Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50516107 (CHEMBL4591083) Show SMILES COc1ccc(NC(=O)[C@@H]2CCN([C@H](C)C2)c2ncccc2Br)cc1Cl |r| Show InChI InChI=1S/C19H21BrClN3O2/c1-12-10-13(7-9-24(12)18-15(20)4-3-8-22-18)19(25)23-14-5-6-17(26-2)16(21)11-14/h3-6,8,11-13H,7,9-10H2,1-2H3,(H,23,25)/t12-,13-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Non-competitive inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus in...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743 BindingDB Entry DOI: 10.7270/Q2DV1P7R
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453058 (US10711036, Compound 116) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H34BrFN6O4/c1-14(2)20(31-21(34)15-7-9-16(25)10-8-15)23(36)32-12-4-6-18(32)22(35)30-17(19(33)13-26)5-3-11-29-24(27)28/h7-10,14,17-18,20H,3-6,11-13H2,1-2H3,(H,30,35)(H,31,34)(H4,27,28,29)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453106 (US10711036, Compound 160) Show SMILES CC(C)[C@H](NC(=O)c1ccc(F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H34F2N6O4/c1-14(2)20(31-21(34)15-7-9-16(26)10-8-15)23(36)32-12-4-6-18(32)22(35)30-17(19(33)13-25)5-3-11-29-24(27)28/h7-10,14,17-18,20H,3-6,11-13H2,1-2H3,(H,30,35)(H,31,34)(H4,27,28,29)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453091 (US10711036, Compound 146) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)c(c1)C#N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H33BrFN7O4/c1-14(2)21(33-22(36)15-7-8-17(26)16(11-15)13-28)24(38)34-10-4-6-19(34)23(37)32-18(20(35)12-27)5-3-9-31-25(29)30/h7-8,11,14,18-19,21H,3-6,9-10,12H2,1-2H3,(H,32,37)(H,33,36)(H4,29,30,31)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453094 (US10711036, Compound 148) Show SMILES CC(C)[C@H](NC(=O)c1cccc(OC(F)(F)F)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H34F4N6O5/c1-14(2)20(34-21(37)15-6-3-7-16(12-15)40-25(27,28)29)23(39)35-11-5-9-18(35)22(38)33-17(19(36)13-26)8-4-10-32-24(30)31/h3,6-7,12,14,17-18,20H,4-5,8-11,13H2,1-2H3,(H,33,38)(H,34,37)(H4,30,31,32)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453124 (US10711036, Compound 174) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N1COC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C23H32BrFN6O5/c1-13(2)19(30-20(33)14-5-7-15(24)8-6-14)22(35)31-12-36-11-17(31)21(34)29-16(18(32)10-25)4-3-9-28-23(26)27/h5-8,13,16-17,19H,3-4,9-12H2,1-2H3,(H,29,34)(H,30,33)(H4,26,27,28)/t16-,17-,19-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453112 (US10711036, Compound 163) Show SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C27H41FN6O4/c1-16(2)18-9-11-19(12-10-18)24(36)33-23(17(3)4)26(38)34-14-6-8-21(34)25(37)32-20(22(35)15-28)7-5-13-31-27(29)30/h9-12,16-17,20-21,23H,5-8,13-15H2,1-4H3,(H,32,37)(H,33,36)(H4,29,30,31)/t20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453119 (US10711036, Compound 169) Show SMILES CC(C)[C@H](NC(=O)OCc1cccc(Cl)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H36ClFN6O5/c1-15(2)21(32-25(37)38-14-16-6-3-7-17(26)12-16)23(36)33-11-5-9-19(33)22(35)31-18(20(34)13-27)8-4-10-30-24(28)29/h3,6-7,12,15,18-19,21H,4-5,8-11,13-14H2,1-2H3,(H,31,35)(H,32,37)(H4,28,29,30)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453116 (US10711036, Compound 167) Show SMILES CC(C)[C@H](NC(=O)Nc1ccccc1Cl)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H35ClFN7O4/c1-14(2)20(32-24(37)31-16-8-4-3-7-15(16)25)22(36)33-12-6-10-18(33)21(35)30-17(19(34)13-26)9-5-11-29-23(27)28/h3-4,7-8,14,17-18,20H,5-6,9-13H2,1-2H3,(H,30,35)(H4,27,28,29)(H2,31,32,37)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453093 (US10711036, Compound 147) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Cl)c(c1)C#N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H33ClFN7O4/c1-14(2)21(33-22(36)15-7-8-17(26)16(11-15)13-28)24(38)34-10-4-6-19(34)23(37)32-18(20(35)12-27)5-3-9-31-25(29)30/h7-8,11,14,18-19,21H,3-6,9-10,12H2,1-2H3,(H,32,37)(H,33,36)(H4,29,30,31)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453114 (US10711036, Compound 165) Show SMILES CC(C)[C@H](NC(=O)Nc1cccc(Cl)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H35ClFN7O4/c1-14(2)20(32-24(37)30-16-7-3-6-15(25)12-16)22(36)33-11-5-9-18(33)21(35)31-17(19(34)13-26)8-4-10-29-23(27)28/h3,6-7,12,14,17-18,20H,4-5,8-11,13H2,1-2H3,(H,31,35)(H4,27,28,29)(H2,30,32,37)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453120 (US10711036, Compound 170) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1Cl)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H36ClFN6O5/c1-15(2)21(32-25(37)38-14-16-7-3-4-8-17(16)26)23(36)33-12-6-10-19(33)22(35)31-18(20(34)13-27)9-5-11-30-24(28)29/h3-4,7-8,15,18-19,21H,5-6,9-14H2,1-2H3,(H,31,35)(H,32,37)(H4,28,29,30)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453089 (US10711036, Compound 145) Show SMILES CC(C)[C@H](NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H34F4N6O5/c1-14(2)20(34-21(37)15-7-9-16(10-8-15)40-25(27,28)29)23(39)35-12-4-6-18(35)22(38)33-17(19(36)13-26)5-3-11-32-24(30)31/h7-10,14,17-18,20H,3-6,11-13H2,1-2H3,(H,33,38)(H,34,37)(H4,30,31,32)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453127 (US10711036, Compound 177) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF)C#N |r| Show InChI InChI=1S/C25H33BrFN7O4/c1-14(2)21(33-22(36)16-5-7-17(26)8-6-16)24(38)34-13-15(12-28)10-19(34)23(37)32-18(20(35)11-27)4-3-9-31-25(29)30/h5-8,14-15,18-19,21H,3-4,9-11,13H2,1-2H3,(H,32,37)(H,33,36)(H4,29,30,31)/t15-,18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453130 (US10711036, Compound 180) Show SMILES CCC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C26H39FN6O5/c1-3-17(2)22(32-26(37)38-16-18-9-5-4-6-10-18)24(36)33-14-8-12-20(33)23(35)31-19(21(34)15-27)11-7-13-30-25(28)29/h4-6,9-10,17,19-20,22H,3,7-8,11-16H2,1-2H3,(H,31,35)(H,32,37)(H4,28,29,30)/t17?,19-,20-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453083 (US10711036, Compound 137) Show SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)-c1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C30H39FN6O4/c1-19(2)26(36-27(39)22-14-12-21(13-15-22)20-8-4-3-5-9-20)29(41)37-17-7-11-24(37)28(40)35-23(25(38)18-31)10-6-16-34-30(32)33/h3-5,8-9,12-15,19,23-24,26H,6-7,10-11,16-18H2,1-2H3,(H,35,40)(H,36,39)(H4,32,33,34)/t23-,24-,26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453118 (US10711036, Compound 168) Show SMILES CC(C)[C@H](NC(=O)OCc1ccc(Cl)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H36ClFN6O5/c1-15(2)21(32-25(37)38-14-16-7-9-17(26)10-8-16)23(36)33-12-4-6-19(33)22(35)31-18(20(34)13-27)5-3-11-30-24(28)29/h7-10,15,18-19,21H,3-6,11-14H2,1-2H3,(H,31,35)(H,32,37)(H4,28,29,30)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453122 (US10711036, Compound 172) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)c1ccc(Br)cc1)C1CCCCC1)C(=O)CF |r| Show InChI InChI=1S/C27H38BrFN6O5/c28-18-10-8-17(9-11-18)24(38)34-23(16-5-2-1-3-6-16)26(40)35-15-19(36)13-21(35)25(39)33-20(22(37)14-29)7-4-12-32-27(30)31/h8-11,16,19-21,23,36H,1-7,12-15H2,(H,33,39)(H,34,38)(H4,30,31,32)/t19-,20+,21+,23+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453099 (US10711036, Compound 154) Show SMILES CC(C)[C@H](NC(=O)\C=C\c1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C26H37FN6O4/c1-17(2)23(32-22(35)13-12-18-8-4-3-5-9-18)25(37)33-15-7-11-20(33)24(36)31-19(21(34)16-27)10-6-14-30-26(28)29/h3-5,8-9,12-13,17,19-20,23H,6-7,10-11,14-16H2,1-2H3,(H,31,36)(H,32,35)(H4,28,29,30)/b13-12+/t19-,20-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453050 (US10711036, Compound 108) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C1CCCCC1)C(=O)CF |r| Show InChI InChI=1S/C29H43FN6O5/c30-18-24(37)22(14-9-16-33-28(31)32)34-26(38)23-15-7-8-17-36(23)27(39)25(21-12-5-2-6-13-21)35-29(40)41-19-20-10-3-1-4-11-20/h1,3-4,10-11,21-23,25H,2,5-9,12-19H2,(H,34,38)(H,35,40)(H4,31,32,33)/t22-,23-,25-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453128 (US10711036, Compound 178) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C22H32BrFN6O4/c1-12(2)18(30-20(33)14-6-8-15(23)9-7-14)21(34)28-13(3)19(32)29-16(17(31)11-24)5-4-10-27-22(25)26/h6-9,12-13,16,18H,4-5,10-11H2,1-3H3,(H,28,34)(H,29,32)(H,30,33)(H4,25,26,27)/t13-,16-,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453080 (US10711036, Compound 134) Show SMILES CC(C)[C@H](NC(=O)c1cccc(c1)C#N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H34FN7O4/c1-15(2)21(32-22(35)17-7-3-6-16(12-17)14-27)24(37)33-11-5-9-19(33)23(36)31-18(20(34)13-26)8-4-10-30-25(28)29/h3,6-7,12,15,18-19,21H,4-5,8-11,13H2,1-2H3,(H,31,36)(H,32,35)(H4,28,29,30)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453055 (US10711036, Compound 113) Show SMILES CC(C)[C@H](NC(=O)c1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H35FN6O4/c1-15(2)20(30-21(33)16-8-4-3-5-9-16)23(35)31-13-7-11-18(31)22(34)29-17(19(32)14-25)10-6-12-28-24(26)27/h3-5,8-9,15,17-18,20H,6-7,10-14H2,1-2H3,(H,29,34)(H,30,33)(H4,26,27,28)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453049 (US10711036, Compound 107) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C26H39FN6O5/c1-17(2)22(32-26(37)38-16-18-9-4-3-5-10-18)24(36)33-14-7-6-12-20(33)23(35)31-19(21(34)15-27)11-8-13-30-25(28)29/h3-5,9-10,17,19-20,22H,6-8,11-16H2,1-2H3,(H,31,35)(H,32,37)(H4,28,29,30)/t19-,20-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50510284 (CHEMBL4461333 | US10711036, Compound 101) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H37FN6O5/c1-16(2)21(31-25(36)37-15-17-8-4-3-5-9-17)23(35)32-13-7-11-19(32)22(34)30-18(20(33)14-26)10-6-12-29-24(27)28/h3-5,8-9,16,18-19,21H,6-7,10-15H2,1-2H3,(H,30,34)(H,31,36)(H4,27,28,29)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM50510284 (CHEMBL4461333 | US10711036, Compound 101) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H37FN6O5/c1-16(2)21(31-25(36)37-15-17-8-4-3-5-9-17)23(35)32-13-7-11-19(32)22(34)30-18(20(33)14-26)10-6-12-29-24(27)28/h3-5,8-9,16,18-19,21H,6-7,10-15H2,1-2H3,(H,30,34)(H,31,36)(H4,27,28,29)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of recombinant LZ-fused MALT1 (340 to 789 residues) (unknown origin) using Ac-LRSR-AMC as substrate by fluorescence assay				Bioorg Med Chem Lett 29: 1336-1339 (2019) Article DOI: 10.1016/j.bmcl.2019.03.046 BindingDB Entry DOI: 10.7270/Q2WW7N1M
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453133 (US10711036, Compound 183) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H36BrFN6O4/c1-14(2)21(32-22(35)17-9-8-16(26)12-15(17)3)24(37)33-11-5-7-19(33)23(36)31-18(20(34)13-27)6-4-10-30-25(28)29/h8-9,12,14,18-19,21H,4-7,10-11,13H2,1-3H3,(H,31,36)(H,32,35)(H4,28,29,30)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453102 (US10711036, Compound 156) Show SMILES CC(C)[C@H](NC(=O)c1cnc2ccccc2c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C27H36FN7O4/c1-16(2)23(34-24(37)18-13-17-7-3-4-8-19(17)32-15-18)26(39)35-12-6-10-21(35)25(38)33-20(22(36)14-28)9-5-11-31-27(29)30/h3-4,7-8,13,15-16,20-21,23H,5-6,9-12,14H2,1-2H3,(H,33,38)(H,34,37)(H4,29,30,31)/t20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453057 (US10711036, Compound 115) Show SMILES CC(C)[C@H](NC(=O)c1cccc(Br)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H34BrFN6O4/c1-14(2)20(31-21(34)15-6-3-7-16(25)12-15)23(36)32-11-5-9-18(32)22(35)30-17(19(33)13-26)8-4-10-29-24(27)28/h3,6-7,12,14,17-18,20H,4-5,8-11,13H2,1-2H3,(H,30,35)(H,31,34)(H4,27,28,29)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453059 (US10711036, Compound 117) Show SMILES CC(C)[C@H](NC(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H37FN6O4/c1-16(2)22(31-21(34)14-17-8-4-3-5-9-17)24(36)32-13-7-11-19(32)23(35)30-18(20(33)15-26)10-6-12-29-25(27)28/h3-5,8-9,16,18-19,22H,6-7,10-15H2,1-2H3,(H,30,35)(H,31,34)(H4,27,28,29)/t18-,19-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453044 (US10711036, Compound 103) Show SMILES CC(C)(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C26H39FN6O5/c1-26(2,3)21(32-25(37)38-16-17-9-5-4-6-10-17)23(36)33-14-8-12-19(33)22(35)31-18(20(34)15-27)11-7-13-30-24(28)29/h4-6,9-10,18-19,21H,7-8,11-16H2,1-3H3,(H,31,35)(H,32,37)(H4,28,29,30)/t18-,19-,21+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453061 (US10711036, Compound 119) Show SMILES CC(C)[C@H](NC(=O)CCc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C26H39FN6O4/c1-17(2)23(32-22(35)13-12-18-8-4-3-5-9-18)25(37)33-15-7-11-20(33)24(36)31-19(21(34)16-27)10-6-14-30-26(28)29/h3-5,8-9,17,19-20,23H,6-7,10-16H2,1-2H3,(H,31,36)(H,32,35)(H4,28,29,30)/t19-,20-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453041 (US10711036, Compound 102) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C1CCCCC1)C(=O)CF |r| Show InChI InChI=1S/C28H41FN6O5/c29-17-23(36)21(13-7-15-32-27(30)31)33-25(37)22-14-8-16-35(22)26(38)24(20-11-5-2-6-12-20)34-28(39)40-18-19-9-3-1-4-10-19/h1,3-4,9-10,20-22,24H,2,5-8,11-18H2,(H,33,37)(H,34,39)(H4,30,31,32)/t21-,22-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453087 (US10711036, Compound 143) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)c1ccc(Br)cc1)C1CCCCC1)C(=O)CF |r| Show InChI InChI=1S/C27H38BrFN6O4/c28-19-12-10-18(11-13-19)24(37)34-23(17-6-2-1-3-7-17)26(39)35-15-5-9-21(35)25(38)33-20(22(36)16-29)8-4-14-32-27(30)31/h10-13,17,20-21,23H,1-9,14-16H2,(H,33,38)(H,34,37)(H4,30,31,32)/t20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453110 (US10711036, Compound 162) Show SMILES CC(C)[C@H](NC(=O)c1ccc(cc1)C(C)(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C28H43FN6O4/c1-17(2)23(34-24(37)18-10-12-19(13-11-18)28(3,4)5)26(39)35-15-7-9-21(35)25(38)33-20(22(36)16-29)8-6-14-32-27(30)31/h10-13,17,20-21,23H,6-9,14-16H2,1-5H3,(H,33,38)(H,34,37)(H4,30,31,32)/t20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453060 (US10711036, Compound 118) Show SMILES CC(C)[C@H](NC(=O)Cc1cccc(Br)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H36BrFN6O4/c1-15(2)22(32-21(35)13-16-6-3-7-17(26)12-16)24(37)33-11-5-9-19(33)23(36)31-18(20(34)14-27)8-4-10-30-25(28)29/h3,6-7,12,15,18-19,22H,4-5,8-11,13-14H2,1-2H3,(H,31,36)(H,32,35)(H4,28,29,30)/t18-,19-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453123 (US10711036, Compound 173) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)c1ccc(Br)cc1)C1CCCCC1)C(=O)CF |r| Show InChI InChI=1S/C25H36BrFN6O5/c26-17-10-8-16(9-11-17)22(36)33-21(15-5-2-1-3-6-15)24(38)32-19(14-34)23(37)31-18(20(35)13-27)7-4-12-30-25(28)29/h8-11,15,18-19,21,34H,1-7,12-14H2,(H,31,37)(H,32,38)(H,33,36)(H4,28,29,30)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453097 (US10711036, Compound 152) Show SMILES CC(C)[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C28H37FN6O4/c1-17(2)24(34-25(37)20-12-11-18-7-3-4-8-19(18)15-20)27(39)35-14-6-10-22(35)26(38)33-21(23(36)16-29)9-5-13-32-28(30)31/h3-4,7-8,11-12,15,17,21-22,24H,5-6,9-10,13-14,16H2,1-2H3,(H,33,38)(H,34,37)(H4,30,31,32)/t21-,22-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453052 (US10711036, Compound 110) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1C[C@@H](O)C[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H37FN6O6/c1-15(2)21(31-25(37)38-14-16-7-4-3-5-8-16)23(36)32-13-17(33)11-19(32)22(35)30-18(20(34)12-26)9-6-10-29-24(27)28/h3-5,7-8,15,17-19,21,33H,6,9-14H2,1-2H3,(H,30,35)(H,31,37)(H4,27,28,29)/t17-,18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453065 (US10711036, Compound 123) Show SMILES COc1ccc(cc1)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H37FN6O5/c1-15(2)21(31-22(34)16-8-10-17(37-3)11-9-16)24(36)32-13-5-7-19(32)23(35)30-18(20(33)14-26)6-4-12-29-25(27)28/h8-11,15,18-19,21H,4-7,12-14H2,1-3H3,(H,30,35)(H,31,34)(H4,27,28,29)/t18-,19-,21-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453121 (US10711036, Compound 171) Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H34BrFN6O5/c1-13(2)20(31-21(35)14-5-7-15(25)8-6-14)23(37)32-12-16(33)10-18(32)22(36)30-17(19(34)11-26)4-3-9-29-24(27)28/h5-8,13,16-18,20,33H,3-4,9-12H2,1-2H3,(H,30,36)(H,31,35)(H4,27,28,29)/t16-,17+,18+,20+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453071 (US10711036, Compound 129) Show SMILES CC(C)[C@H](NC(=O)Nc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H36FN7O4/c1-15(2)20(31-24(36)29-16-8-4-3-5-9-16)22(35)32-13-7-11-18(32)21(34)30-17(19(33)14-25)10-6-12-28-23(26)27/h3-5,8-9,15,17-18,20H,6-7,10-14H2,1-2H3,(H,30,34)(H4,26,27,28)(H2,29,31,36)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453067 (US10711036, Compound 125) Show SMILES CC(C)[C@H](NC(=O)c1csc(C)n1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C22H34FN7O4S/c1-12(2)18(29-19(32)15-11-35-13(3)27-15)21(34)30-9-5-7-16(30)20(33)28-14(17(31)10-23)6-4-8-26-22(24)25/h11-12,14,16,18H,4-10H2,1-3H3,(H,28,33)(H,29,32)(H4,24,25,26)/t14-,16-,18-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453051 (US10711036, Compound 109) Show SMILES CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N1C[C@H](O)C[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C25H37FN6O6/c1-15(2)21(31-25(37)38-14-16-7-4-3-5-8-16)23(36)32-13-17(33)11-19(32)22(35)30-18(20(34)12-26)9-6-10-29-24(27)28/h3-5,7-8,15,17-19,21,33H,6,9-14H2,1-2H3,(H,30,35)(H,31,37)(H4,27,28,29)/t17-,18+,19+,21+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453079 (US10711036, Compound 133) Show SMILES CC(C)[C@H](NC(=O)c1cccc(NC(C)=O)c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C26H38FN7O5/c1-15(2)22(33-23(37)17-7-4-8-18(13-17)31-16(3)35)25(39)34-12-6-10-20(34)24(38)32-19(21(36)14-27)9-5-11-30-26(28)29/h4,7-8,13,15,19-20,22H,5-6,9-12,14H2,1-3H3,(H,31,35)(H,32,38)(H,33,37)(H4,28,29,30)/t19-,20-,22-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453101 (US10711036, Compound 155) Show SMILES CC(C)[C@H](NC(=O)c1ccc2ccccc2n1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C27H36FN7O4/c1-16(2)23(34-24(37)20-12-11-17-7-3-4-8-18(17)32-20)26(39)35-14-6-10-21(35)25(38)33-19(22(36)15-28)9-5-13-31-27(29)30/h3-4,7-8,11-12,16,19,21,23H,5-6,9-10,13-15H2,1-2H3,(H,33,38)(H,34,37)(H4,29,30,31)/t19-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453047 (US10711036, Compound 105) Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)c1cccnc1)C(=O)CF |r| Show InChI InChI=1S/C27H34FN7O5/c28-15-22(36)20(10-5-13-32-26(29)30)33-24(37)21-11-6-14-35(21)25(38)23(19-9-4-12-31-16-19)34-27(39)40-17-18-7-2-1-3-8-18/h1-4,7-9,12,16,20-21,23H,5-6,10-11,13-15,17H2,(H,33,37)(H,34,39)(H4,29,30,32)/t20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453062 (US10711036, Compound 120) Show SMILES CC(C)[C@H](NC(=O)C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H41FN6O4/c1-15(2)20(30-21(33)16-8-4-3-5-9-16)23(35)31-13-7-11-18(31)22(34)29-17(19(32)14-25)10-6-12-28-24(26)27/h15-18,20H,3-14H2,1-2H3,(H,29,34)(H,30,33)(H4,26,27,28)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453076 (US10711036, Compound 131) Show SMILES CC(C)[C@H](NC(=O)c1cccc(c1)N1CCOCC1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C28H42FN7O5/c1-18(2)24(34-25(38)19-6-3-7-20(16-19)35-12-14-41-15-13-35)27(40)36-11-5-9-22(36)26(39)33-21(23(37)17-29)8-4-10-32-28(30)31/h3,6-7,16,18,21-22,24H,4-5,8-15,17H2,1-2H3,(H,33,39)(H,34,38)(H4,30,31,32)/t21-,22-,24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM453103 (US10711036, Compound 157) Show SMILES CC(C)[C@H](NC(=O)c1ccc2cnccc2c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C27H36FN7O4/c1-16(2)23(34-24(37)18-7-8-19-15-31-11-9-17(19)13-18)26(39)35-12-4-6-21(35)25(38)33-20(22(36)14-28)5-3-10-32-27(29)30/h7-9,11,13,15-16,20-21,23H,3-6,10,12,14H2,1-2H3,(H,33,38)(H,34,37)(H4,29,30,32)/t20-,21-,23-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020) BindingDB Entry DOI: 10.7270/Q2H70JVH
					More data for this Ligand-Target Pair

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