null
SMILES: NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCCN1C(=O)[C@@H](NC(=O)OCc1ccccc1)C1CCCCC1)C(=O)CF
InChI Key: InChIKey=GINPNDWKVJLVFK-LSQMVHIFSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human)) | BDBM453050 (US10711036, Compound 108) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent | Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa... | US Patent US10711036 (2020) | |||||||||||
More data for this Ligand-Target Pair |