BDBM453116 US10711036, Compound 167

SMILES: CC(C)[C@H](NC(=O)Nc1ccccc1Cl)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF

InChI Key: InChIKey=YRJPPGHUHXGEBS-BJLQDIEVSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453116   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM453116 (US10711036, Compound 167) Show SMILES CC(C)[C@H](NC(=O)Nc1ccccc1Cl)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r| Show InChI InChI=1S/C24H35ClFN7O4/c1-14(2)20(32-24(37)31-16-8-4-3-7-15(16)25)22(36)33-12-6-10-18(33)21(35)30-17(19(34)13-26)9-5-11-29-23(27)28/h3-4,7-8,14,17-18,20H,5-6,9-13H2,1-2H3,(H,30,35)(H4,27,28,29)(H2,31,32,37)/t17-,18-,20-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation US Patent					Assay Description For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...				US Patent US10711036 (2020)
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