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SMILES: CC(C)[C@H](NC(=O)c1ccc(Br)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF

InChI Key: InChIKey=UJLWPBJAKVXFEM-ZJOUEHCJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453133   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM453133
PNG
(US10711036, Compound 183)
Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r|
Show InChI InChI=1S/C25H36BrFN6O4/c1-14(2)21(32-22(35)17-9-8-16(26)12-15(17)3)24(37)33-11-5-7-19(33)23(36)31-18(20(34)13-27)6-4-10-30-25(28)29/h8-9,12,14,18-19,21H,4-7,10-11,13H2,1-3H3,(H,31,36)(H,32,35)(H4,28,29,30)/t18-,19-,21-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
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PC cid
PC sid
UniChem
US Patent
 40n/an/an/an/an/an/an/an/a



Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation

US Patent


Assay Description
For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...

US Patent US10711036 (2020)

More data for this
Ligand-Target Pair