BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM453122'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM453122
PNG
(US10711036, Compound 172)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)c1ccc(Br)cc1)C1CCCCC1)C(=O)CF |r|
Show InChI InChI=1S/C27H38BrFN6O5/c28-18-10-8-17(9-11-18)24(38)34-23(16-5-2-1-3-6-16)26(40)35-15-19(36)13-21(35)25(39)33-20(22(37)14-29)7-4-12-32-27(30)31/h8-11,16,19-21,23,36H,1-7,12-15H2,(H,33,39)(H,34,38)(H4,30,31,32)/t19-,20+,21+,23+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
US Patent
 34n/an/an/an/an/an/an/an/a



Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation

US Patent


Assay Description
For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...

US Patent US10711036 (2020)


BindingDB Entry DOI: 10.7270/Q2H70JVH
More data for this
Ligand-Target Pair