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SMILES: CC(C)[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF

InChI Key: InChIKey=VMMYGLODFBXXHS-FIXSFTCYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453097   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM453097
PNG
(US10711036, Compound 152)
Show SMILES CC(C)[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF |r|
Show InChI InChI=1S/C28H37FN6O4/c1-17(2)24(34-25(37)20-12-11-18-7-3-4-8-19(18)15-20)27(39)35-14-6-10-22(35)26(38)33-21(23(36)16-29)9-5-13-32-28(30)31/h3-4,7-8,11-12,15,17,21-22,24H,5-6,9-10,13-14,16H2,1-2H3,(H,33,38)(H,34,37)(H4,30,31,32)/t21-,22-,24-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 47n/an/an/an/an/an/an/an/a



Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation

US Patent


Assay Description
For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...

US Patent US10711036 (2020)

More data for this
Ligand-Target Pair