BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM453127'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))		BDBM453127
PNG
(US10711036, Compound 177)
Show SMILES CC(C)[C@H](NC(=O)c1ccc(Br)cc1)C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)CF)C#N |r|
Show InChI InChI=1S/C25H33BrFN7O4/c1-14(2)21(33-22(36)16-5-7-17(26)8-6-16)24(38)34-13-15(12-28)10-19(34)23(37)32-18(20(35)11-27)4-3-9-31-25(29)30/h5-8,14-15,18-19,21H,3-4,9-11,13H2,1-2H3,(H,32,37)(H,33,36)(H4,29,30,31)/t15-,18-,19-,21-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 28n/an/an/an/an/an/an/an/a



Cornell University; Dana-Farber Cancer Institute, Inc.; Children''s Medical Center Corporation

US Patent


Assay Description
For exemplary compounds of the disclosure, Ki for inhibition of MALT1 was measured (Table E11). A concentration of 100 nM MALT1 was used for the assa...

US Patent US10711036 (2020)


BindingDB Entry DOI: 10.7270/Q2H70JVH
More data for this
Ligand-Target Pair