BDBM50516105 CHEMBL4470809

SMILES: Clc1cccnc1N1CCC(CC1)C(=O)Nc1cnc(OC2CC2)c(Cl)c1

InChI Key: InChIKey=BBFKTYQGWOPGCG-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516105   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50516105 (CHEMBL4470809) Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1cnc(OC2CC2)c(Cl)c1 Show InChI InChI=1S/C19H20Cl2N4O2/c20-15-2-1-7-22-17(15)25-8-5-12(6-9-25)18(26)24-13-10-16(21)19(23-11-13)27-14-3-4-14/h1-2,7,10-12,14H,3-6,8-9H2,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743
					More data for this Ligand-Target Pair