BDBM50516126 CHEMBL4460951

SMILES: COc1cnc(NC(=O)C2CCN(CC2)c2ncccc2Cl)cc1Cl

InChI Key: InChIKey=PHYHSESPZMAUPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50516126 (CHEMBL4460951) Show SMILES COc1cnc(NC(=O)C2CCN(CC2)c2ncccc2Cl)cc1Cl Show InChI InChI=1S/C17H18Cl2N4O2/c1-25-14-10-21-15(9-13(14)19)22-17(24)11-4-7-23(8-5-11)16-12(18)3-2-6-20-16/h2-3,6,9-11H,4-5,7-8H2,1H3,(H,21,22,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743
					More data for this Ligand-Target Pair