BDBM50516130 CHEMBL4594202

SMILES: COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C(F)(F)F)cc1Cl

InChI Key: InChIKey=TVBNOOJZTIOFTN-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50516130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
MALT lymphoma-associated translocation (MALT1) (Homo sapiens (Human))	BDBM50516130 (CHEMBL4594202) Show SMILES COc1ccc(NC(=O)C2CCN(CC2)c2ncccc2C(F)(F)F)cc1Cl Show InChI InChI=1S/C19H19ClF3N3O2/c1-28-16-5-4-13(11-15(16)20)25-18(27)12-6-9-26(10-7-12)17-14(19(21,22)23)3-2-8-24-17/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,25,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, LLC Curated by ChEMBL					Assay Description Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...				Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126743
					More data for this Ligand-Target Pair