BDBM50519115 CHEMBL4562446

SMILES: C[C@@H](NC(=O)c1cc2ccccc2n1C)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=DVWXKBSQGDCQEW-GFCCVEGCSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50519115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D-3-phosphoglycerate dehydrogenase (Homo sapiens (Human))	BDBM50519115 (CHEMBL4562446) Show SMILES C[C@@H](NC(=O)c1cc2ccccc2n1C)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C19H18N2O3/c1-12(13-7-9-14(10-8-13)19(23)24)20-18(22)17-11-15-5-3-4-6-16(15)21(17)2/h3-12H,1-2H3,(H,20,22)(H,23,24)/t12-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim RCV GmbH & Co. KG Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged human PHGDH (4 to 315 residues) assessed as effect on NADH fluorescence incubated for 2 hrs using 3-PG substrate...				J Med Chem 62: 7976-7997 (2019) Article DOI: 10.1021/acs.jmedchem.9b00718
					More data for this Ligand-Target Pair