BDBM50527945 CHEMBL4527801

SMILES: CC(=O)Nc1cccc(c1)-c1cncc(\C=C2/SC(=N)NC2=O)c1

InChI Key: InChIKey=IOVDIWPOZDYYSY-UUASQNMZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527945   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha (Homo sapiens)	BDBM50527945 (CHEMBL4527801) Show SMILES CC(=O)Nc1cccc(c1)-c1cncc(\C=C2/SC(=N)NC2=O)c1 Show InChI InChI=1S/C17H14N4O2S/c1-10(22)20-14-4-2-3-12(7-14)13-5-11(8-19-9-13)6-15-16(23)21-17(18)24-15/h2-9H,1H3,(H,20,22)(H2,18,21,23)/b15-6-	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay				J Med Chem 63: 4880-4895 (2020) Article DOI: 10.1021/acs.jmedchem.0c00227
					More data for this Ligand-Target Pair
Phosphatidylinositol-5-phosphate 4-kinase type-2 beta (Homo sapiens (Human))	BDBM50527945 (CHEMBL4527801) Show SMILES CC(=O)Nc1cccc(c1)-c1cncc(\C=C2/SC(=N)NC2=O)c1 Show InChI InChI=1S/C17H14N4O2S/c1-10(22)20-14-4-2-3-12(7-14)13-5-11(8-19-9-13)6-15-16(23)21-17(18)24-15/h2-9H,1H3,(H,20,22)(H2,18,21,23)/b15-6-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay				J Med Chem 63: 4880-4895 (2020) Article DOI: 10.1021/acs.jmedchem.0c00227
					More data for this Ligand-Target Pair