BDBM50527948 CHEMBL4440465

SMILES: CS(=O)(=O)Nc1ccc(cc1)-c1cncc(c1)-c1ccc2cc[nH]c2c1

InChI Key: InChIKey=OCQOLFRRSJQDMD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50527948   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol-5-phosphate 4-kinase type-2 alpha (Homo sapiens)	BDBM50527948 (CHEMBL4440465) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cncc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C20H17N3O2S/c1-26(24,25)23-19-6-4-14(5-7-19)17-10-18(13-21-12-17)16-3-2-15-8-9-22-20(15)11-16/h2-13,22-23H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant PI5P4Kalpha (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay				J Med Chem 63: 4880-4895 (2020) Article DOI: 10.1021/acs.jmedchem.0c00227
					More data for this Ligand-Target Pair
Phosphatidylinositol-5-phosphate 4-kinase type-2 beta (Homo sapiens (Human))	BDBM50527948 (CHEMBL4440465) Show SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cncc(c1)-c1ccc2cc[nH]c2c1 Show InChI InChI=1S/C20H17N3O2S/c1-26(24,25)23-19-6-4-14(5-7-19)17-10-18(13-21-12-17)16-3-2-15-8-9-22-20(15)11-16/h2-13,22-23H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dana-Farber Cancer Institute Curated by ChEMBL					Assay Description Inhibition of GST-tagged recombinant PI5P4Kbeta (unknown origin) incubated for 1 hr in presence of DPPS and PI5P by ADP-Glo assay				J Med Chem 63: 4880-4895 (2020) Article DOI: 10.1021/acs.jmedchem.0c00227
					More data for this Ligand-Target Pair