BDBM50529875 CHEMBL4580000

SMILES: Fc1ccc(cc1)-c1ccncc1\C=C\C(=O)Nc1ccc(CCc2nnco2)cc1

InChI Key: InChIKey=IICSXHYHGAAWBA-IZZDOVSWSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50529875   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C (Homo sapiens (Human))	BDBM50529875 (CHEMBL4580000) Show SMILES Fc1ccc(cc1)-c1ccncc1\C=C\C(=O)Nc1ccc(CCc2nnco2)cc1 Show InChI InChI=1S/C24H19FN4O2/c25-20-7-4-18(5-8-20)22-13-14-26-15-19(22)6-11-23(30)28-21-9-1-17(2-10-21)3-12-24-29-27-16-31-24/h1-2,4-11,13-16H,3,12H2,(H,28,30)/b11-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Shaoxing University Curated by ChEMBL					Assay Description Displacement of Kinase tracer 236 from recombinant full-length human N-terminal GST-fused CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) expre...				Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076
					More data for this Ligand-Target Pair
CDK19/Cyclin C (Homo sapiens (Human))	BDBM50529875 (CHEMBL4580000) Show SMILES Fc1ccc(cc1)-c1ccncc1\C=C\C(=O)Nc1ccc(CCc2nnco2)cc1 Show InChI InChI=1S/C24H19FN4O2/c25-20-7-4-18(5-8-20)22-13-14-26-15-19(22)6-11-23(30)28-21-9-1-17(2-10-21)3-12-24-29-27-16-31-24/h1-2,4-11,13-16H,3,12H2,(H,28,30)/b11-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Shaoxing University Curated by ChEMBL					Assay Description Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay				Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076
					More data for this Ligand-Target Pair
CDK19/Cyclin C (Homo sapiens (Human))	BDBM50529875 (CHEMBL4580000) Show SMILES Fc1ccc(cc1)-c1ccncc1\C=C\C(=O)Nc1ccc(CCc2nnco2)cc1 Show InChI InChI=1S/C24H19FN4O2/c25-20-7-4-18(5-8-20)22-13-14-26-15-19(22)6-11-23(30)28-21-9-1-17(2-10-21)3-12-24-29-27-16-31-24/h1-2,4-11,13-16H,3,12H2,(H,28,30)/b11-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
Shaoxing University Curated by ChEMBL					Assay Description Displacement of Kinase tracer 236 from GST-fused CDK19/cyclin C (unknown origin) after 60 mins by TR-FRET assay				Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50529875 (CHEMBL4580000) Show SMILES Fc1ccc(cc1)-c1ccncc1\C=C\C(=O)Nc1ccc(CCc2nnco2)cc1 Show InChI InChI=1S/C24H19FN4O2/c25-20-7-4-18(5-8-20)22-13-14-26-15-19(22)6-11-23(30)28-21-9-1-17(2-10-21)3-12-24-29-27-16-31-24/h1-2,4-11,13-16H,3,12H2,(H,28,30)/b11-6+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Shaoxing University Curated by ChEMBL					Assay Description Displacement of Kinase tracer 236 from recombinant full-length human N-terminal GST-fused CDK8 (1 to 464 residues)/cyclin C (1 to 283 residues) expre...				Eur J Med Chem 164: 77-91 (2019) Article DOI: 10.1016/j.ejmech.2018.11.076
					More data for this Ligand-Target Pair