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Compile Data Set for Download or QSAR

Found 836 hits Enz. Inhib. hit(s) with Target = 'Cyclin-C'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cyclin-C


(Homo sapiens (Human))
BDBM50567855
PNG
(CHEMBL4871899)
Show SMILES Clc1cncc(-c2ccc(s2)-c2ccccc2)c1N1CCC2(CCNC2=O)CC1
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5n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567870
PNG
(CHEMBL4867449)
Show SMILES Nc1ncc(-c2cc3ccccc3s2)c(N2CCC3(CCNC3=O)CC2)c1Cl
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7n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567848
PNG
(CHEMBL4847659)
Show SMILES Cc1ccsc1-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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8n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50073190
PNG
(CHEMBL3408213 | US11471446, Compound DBA-11)
Show SMILES Cn1cc(cn1)-c1ccc(cc1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
Show InChI InChI=1S/C23H24ClN5O/c1-28-15-18(12-27-28)16-2-4-17(5-3-16)19-13-25-14-20(24)21(19)29-10-7-23(8-11-29)6-9-26-22(23)30/h2-5,12-15H,6-11H2,1H3,(H,26,30)
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9n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cyclin-C


(Homo sapiens (Human))
BDBM50567869
PNG
(CHEMBL4878007)
Show SMILES Nc1ncc(-c2cc3ccccc3o2)c(N2CCC3(CCNC3=O)CC2)c1Cl
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9n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567842
PNG
(CHEMBL4876642)
Show SMILES Clc1cncc(-c2cccs2)c1N1CCC2(CCNC2=O)CC1
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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567850
PNG
(CHEMBL4874260)
Show SMILES Cc1ccc(s1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567849
PNG
(CHEMBL4859146)
Show SMILES Cc1csc(c1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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10n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50163795
PNG
(CHEMBL3798382)
Show SMILES Cn1ncc2cc(ccc12)-c1cnc(N)c(Cl)c1N1CCC2(CCNC2=O)CC1
Show InChI InChI=1S/C21H23ClN6O/c1-27-16-3-2-13(10-14(16)11-26-27)15-12-25-19(23)17(22)18(15)28-8-5-21(6-9-28)4-7-24-20(21)29/h2-3,10-12H,4-9H2,1H3,(H2,23,25)(H,24,29)
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11n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Cyclin-C


(Homo sapiens (Human))
BDBM50567851
PNG
(CHEMBL4878175)
Show SMILES Clc1ccc(s1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563321
PNG
(CHEMBL4744174)
Show SMILES Clc1cncc(-c2c[nH]c3ncccc23)c1N1CCC2(CCNC2=O)CC1
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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563322
PNG
(CHEMBL4777349)
Show SMILES Clc1cncc(-c2cc3ccccc3o2)c1N1CCC2(CCNC2=O)CC1
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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567844
PNG
(CHEMBL4846744)
Show SMILES Clc1cncc(-c2cc[nH]c2)c1N1CCC2(CCNC2=O)CC1
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14n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563310
PNG
(CHEMBL4790136)
Show SMILES Clc1cncc(-c2cccc3ccccc23)c1N1CCC2(CCNC2=O)CC1
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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563313
PNG
(CHEMBL4778713)
Show SMILES Clc1cncc(-c2cccc3c4ccccc4oc23)c1N1CCC2(CCNC2=O)CC1
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16n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567843
PNG
(CHEMBL4865031)
Show SMILES Clc1cncc(-c2ccsc2)c1N1CCC2(CCNC2=O)CC1
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18n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563303
PNG
(CHEMBL4788598)
Show SMILES Clc1cncc(-c2cccc3[nH]ccc23)c1N1CCC2(CCNC2=O)CC1
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19n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563325
PNG
(CHEMBL4743413)
Show SMILES Clc1cncc(-c2csc3ccccc23)c1N1CCC2(CCNC2=O)CC1
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21n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563311
PNG
(CHEMBL4757811)
Show SMILES Cc1ccc(-c2cncc(Cl)c2N2CCC3(CCNC3=O)CC2)c2ccccc12
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22n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563306
PNG
(CHEMBL4798011)
Show SMILES Clc1cncc(-c2cccc3ncccc23)c1N1CCC2(CCNC2=O)CC1
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22n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567845
PNG
(CHEMBL4849022)
Show SMILES Cc1ccc(o1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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22n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563314
PNG
(CHEMBL4783542)
Show SMILES Clc1cncc(-c2cccc3c4ccccc4sc23)c1N1CCC2(CCNC2=O)CC1
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24n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563312
PNG
(CHEMBL4780807)
Show SMILES COc1ccc(-c2cncc(Cl)c2N2CCC3(CCNC3=O)CC2)c2ccccc12
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26n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567840
PNG
(CHEMBL4864207)
Show SMILES Clc1cncc(-c2ccco2)c1N1CCC2(CCNC2=O)CC1
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26n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567860
PNG
(CHEMBL4865441)
Show SMILES Cn1cccc1-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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30n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567858
PNG
(CHEMBL4878338)
Show SMILES Clc1cncc(-c2ccc(CN3CCOCC3)s2)c1N1CCC2(CCNC2=O)CC1
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32n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567847
PNG
(CHEMBL4858621)
Show SMILES CCOCOCc1ccc(o1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
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36n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563296
PNG
(CHEMBL4745572)
Show SMILES Clc1cncc(-c2cnn(c2)-c2ccccc2)c1N1CCC2(CCNC2=O)CC1
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42n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567841
PNG
(CHEMBL4847329)
Show SMILES Clc1cncc(-c2ccoc2)c1N1CCC2(CCNC2=O)CC1
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42n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567859
PNG
(CHEMBL4849792)
Show SMILES CC(C)(C)OC(=O)N1CCN(Cc2ccc(s2)-c2cncc(Cl)c2N2CCC3(CCNC3=O)CC2)CC1
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46n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563323
PNG
(CHEMBL4791586)
Show SMILES Clc1cncc(-c2cc3ccccc3s2)c1N1CCC2(CCNC2=O)CC1
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48n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563320
PNG
(CHEMBL4778461)
Show SMILES Clc1cncc(-c2cn(c3ncccc23)S(=O)(=O)c2ccccc2)c1N1CCC2(CCNC2=O)CC1
PDB

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50n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563307
PNG
(CHEMBL4743572)
Show SMILES Clc1cncc(-c2cccc3cnccc23)c1N1CCC2(CCNC2=O)CC1
PDB

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52n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567865
PNG
(CHEMBL4874881)
Show SMILES Clc1cncc(-c2csc(C=O)c2)c1N1CCC2(CCNC2=O)CC1
PDB

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52n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563302
PNG
(CHEMBL4800651)
Show SMILES Cn1cc2c(cccc2n1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
PDB

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52n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563319
PNG
(CHEMBL4800101)
Show SMILES Clc1cncc(-c2c[nH]c3ccccc23)c1N1CCC2(CCNC2=O)CC1
PDB

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56n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563317
PNG
(CHEMBL4758431)
Show SMILES Clc1cncc(-c2cn(Cc3ccccc3)c3ccccc23)c1N1CCC2(CCNC2=O)CC1
PDB

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58n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567852
PNG
(CHEMBL4853488)
Show SMILES CC(=O)c1ccc(s1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
PDB

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66n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563304
PNG
(CHEMBL4749963)
Show SMILES Clc1cncc(-c2cncc3ccccc23)c1N1CCC2(CCNC2=O)CC1
PDB

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66n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567853
PNG
(CHEMBL4854953)
Show SMILES Clc1cncc(-c2ccc(C=O)s2)c1N1CCC2(CCNC2=O)CC1
PDB

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67n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563316
PNG
(CHEMBL4797631)
Show SMILES Cn1c(cc2ccccc12)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
PDB

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79n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567846
PNG
(CHEMBL4872651)
Show SMILES Clc1cncc(-c2ccc(C=O)o2)c1N1CCC2(CCNC2=O)CC1
PDB

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82n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567868
PNG
(CHEMBL4879053)
Show SMILES FC(F)n1cc(cn1)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
PDB

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93n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567857
PNG
(CHEMBL4873555)
Show SMILES Clc1cncc(-c2ccc(CN3CCCCC3)s2)c1N1CCC2(CCNC2=O)CC1
PDB

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106n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563309
PNG
(CHEMBL4740495)
Show SMILES Clc1cncc(-c2cccc3cccnc23)c1N1CCC2(CCNC2=O)CC1
PDB

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114n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567854
PNG
(CHEMBL4856332)
Show SMILES Cc1cc(sc1C=O)-c1cncc(Cl)c1N1CCC2(CCNC2=O)CC1
PDB

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119n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563298
PNG
(CHEMBL4763695)
Show SMILES Clc1cncc(-c2cnn(c2)N2CCOCC2)c1N1CCC2(CCNC2=O)CC1
PDB

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124n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50567856
PNG
(CHEMBL4867825)
Show SMILES Clc1cncc(-c2ccc(CN3CCCC3)s2)c1N1CCC2(CCNC2=O)CC1
PDB

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132n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/Cyclin C (unknown origin) using RBER-CHKtide as substrate in presence of [32P]gammaATP incubated for 60 mins by microplate scintil...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113391
BindingDB Entry DOI: 10.7270/Q29P35DW
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563305
PNG
(CHEMBL4780661)
Show SMILES Clc1cncc(-c2ccnc3ccccc23)c1N1CCC2(CCNC2=O)CC1
PDB

UniProtKB/SwissProt

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138n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
Cyclin-C


(Homo sapiens (Human))
BDBM50563315
PNG
(CHEMBL4752645)
Show SMILES Clc1cncc(-c2cc3ccccc3[nH]2)c1N1CCC2(CCNC2=O)CC1
PDB

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156n/an/an/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CDK8/cyclin C (unknown origin) using RBER-IRStide as substrate incubated for 60 mins in presence of [gamma33P]ATP by scintillation coun...


Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113248
BindingDB Entry DOI: 10.7270/Q2930XW8
More data for this
Ligand-Target Pair
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