BDBM50531776 CHEMBL4533952

SMILES: O=C(C1CC1)c1ccc(cc1)-n1ccnc1

InChI Key: InChIKey=VOIHFCFHQFRMBF-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50531776   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50531776 (CHEMBL4533952) Show SMILES O=C(C1CC1)c1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C13H12N2O/c16-13(10-1-2-10)11-3-5-12(6-4-11)15-8-7-14-9-15/h3-10H,1-2H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.30	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute (CSIR-CDRI) Curated by ChEMBL					Assay Description Positive allosteric modulation of 5HT2B receptor (unknown origin) expressed in HEK293 cells co-expressing NFAT-RE assessed as increase in serotonin-i...				Eur J Med Chem 164: 499-516 (2019) Article DOI: 10.1016/j.ejmech.2018.12.070
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50531776 (CHEMBL4533952) Show SMILES O=C(C1CC1)c1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C13H12N2O/c16-13(10-1-2-10)11-3-5-12(6-4-11)15-8-7-14-9-15/h3-10H,1-2H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.30	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute (CSIR-CDRI) Curated by ChEMBL					Assay Description Positive allosteric modulation of 5HT2C receptor (unknown origin) expressed in HEK293 cells co-expressing NFAT-RE assessed as increase in serotonin-i...				Eur J Med Chem 164: 499-516 (2019) Article DOI: 10.1016/j.ejmech.2018.12.070
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50531776 (CHEMBL4533952) Show SMILES O=C(C1CC1)c1ccc(cc1)-n1ccnc1 Show InChI InChI=1S/C13H12N2O/c16-13(10-1-2-10)11-3-5-12(6-4-11)15-8-7-14-9-15/h3-10H,1-2H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
CSIR-Central Drug Research Institute (CSIR-CDRI) Curated by ChEMBL					Assay Description Positive allosteric modulation of 5HT2A receptor (unknown origin) expressed in HEK293 cells co-expressing NFAT-RE assessed as increase in serotonin-i...				Eur J Med Chem 164: 499-516 (2019) Article DOI: 10.1016/j.ejmech.2018.12.070
					More data for this Ligand-Target Pair