BDBM50536328 CHEMBL1448756

SMILES: O=C(Nc1ccc(cc1)C(=O)NCC1COc2ccccc2O1)c1ccco1

InChI Key: InChIKey=RCBVVLCKTHDFDY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50536328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536328 (CHEMBL1448756) Show SMILES O=C(Nc1ccc(cc1)C(=O)NCC1COc2ccccc2O1)c1ccco1 Show InChI InChI=1S/C21H18N2O5/c24-20(22-12-16-13-27-17-4-1-2-5-18(17)28-16)14-7-9-15(10-8-14)23-21(25)19-6-3-11-26-19/h1-11,16H,12-13H2,(H,22,24)(H,23,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016
					More data for this Ligand-Target Pair