Compile Data Set for Download or QSAR

Found 152 hits Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase TAO2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human TAOK2 using MBP as substrate by [gamma-33P]-ATP assay				Citation and Details Article DOI: 10.1016/j.bmc.2018.02.022 BindingDB Entry DOI: 10.7270/Q2DJ5KB8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM2579 ((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...) Show SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13 |r| Show InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	11.7	n/a	n/a	n/a	n/a	n/a	n/a
University of Florida Curated by ChEMBL					Assay Description Inhibition of human TAOK2 using MBP as substrate by [gamma-33P]-ATP assay				Eur J Med Chem 161: 456-467 (2019) Article DOI: 10.1016/j.ejmech.2018.10.052 BindingDB Entry DOI: 10.7270/Q2W380MT
					More data for this Ligand-Target Pair				3D Structure (crystal)
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM50244953 (CHEMBL4063500) Show SMILES CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 Show InChI InChI=1S/C28H37N7O4/c1-34(2)27(38)23-17-19-18-29-28(32-26(19)35(23)22-9-7-8-10-22)31-21-15-13-20(14-16-21)30-24(36)11-5-3-4-6-12-25(37)33-39/h13-18,22,39H,3-12H2,1-2H3,(H,30,36)(H,33,37)(H,29,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	84	n/a	n/a	n/a	n/a	n/a	n/a
Nankai University Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal His6-tagged TAO2 expressed in sf21 cells				J Med Chem 61: 3166-3192 (2018) Article DOI: 10.1021/acs.jmedchem.8b00209 BindingDB Entry DOI: 10.7270/Q2KS6TZK
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM50429615 (CHEMBL2334586) Show SMILES CC(C)(O)C#Cc1ccc2[nH]c3CCCc4cnc(N)nc4-c3c2c1 Show InChI InChI=1S/C20H20N4O/c1-20(2,25)9-8-12-6-7-15-14(10-12)17-16(23-15)5-3-4-13-11-22-19(21)24-18(13)17/h6-7,10-11,23,25H,3-5H2,1-2H3,(H2,21,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00697 BindingDB Entry DOI: 10.7270/Q2MP5771
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536316 (CHEMBL4537058) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cc(OC)ccc2OC)n1 Show InChI InChI=1S/C18H20N4O3S2/c1-5-15(23)22-18-19-10(2)16(27-18)13-9-26-17(21-13)20-12-8-11(24-3)6-7-14(12)25-4/h6-9H,5H2,1-4H3,(H,20,21)(H,19,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system using MBP as substrate measured after 30 mins in p...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536316 (CHEMBL4537058) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cc(OC)ccc2OC)n1 Show InChI InChI=1S/C18H20N4O3S2/c1-5-15(23)22-18-19-10(2)16(27-18)13-9-26-17(21-13)20-12-8-11(24-3)6-7-14(12)25-4/h6-9H,5H2,1-4H3,(H,20,21)(H,19,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM50536679 (CHEMBL4568087) Show SMILES Cn1cc(cn1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)N[C@@H]1CCCC[C@@H]1N |r| Show InChI InChI=1S/C21H23N7OS/c1-27-10-15(8-24-27)14-7-23-20-16(9-25-28(20)11-14)13-6-19(30-12-13)21(29)26-18-5-3-2-4-17(18)22/h6-12,17-18H,2-5,22H2,1H3,(H,26,29)/t17-,18+/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Merck and Co. Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged TAOK2 catalytic domain expressed in baculovirus expression system by Z'-LYTE assay				Bioorg Med Chem Lett 26: 4362-6 (2016) Article DOI: 10.1016/j.bmcl.2016.02.003 BindingDB Entry DOI: 10.7270/Q2NP27X5
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM50235830 (CHEMBL2006765) Show SMILES CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3cc[nH]c3n2)cc1 Show InChI InChI=1S/C18H19F3N6O/c1-2-8-23-16(28)11-3-5-12(6-4-11)25-17-26-14-13(7-9-22-14)15(27-17)24-10-18(19,20)21/h3-7,9H,2,8,10H2,1H3,(H,23,28)(H3,22,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	529	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Bioresearch Center Curated by ChEMBL					Assay Description Inhibition of TAOK2 (unknown origin) after 60 mins by TR-FRET assay				Bioorg Med Chem Lett 26: 5562-5567 (2016) Article DOI: 10.1016/j.bmcl.2016.09.077 BindingDB Entry DOI: 10.7270/Q2WQ061V
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536333 (CHEMBL4550547) Show SMILES O=C(NCC1COc2ccccc2O1)c1ccc2CC(=S)N(CC3=CC=CC3)C(=O)c2c1 |c:27,t:25| Show InChI InChI=1S/C25H22N2O4S/c28-24(26-13-19-15-30-21-7-3-4-8-22(21)31-19)18-10-9-17-12-23(32)27(25(29)20(17)11-18)14-16-5-1-2-6-16/h1-5,7-11,19H,6,12-15H2,(H,26,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536313 (CHEMBL4529072) Show SMILES CCOc1ccccc1Nc1nc(cs1)-c1sc(NC(=O)CC)nc1C Show InChI InChI=1S/C18H20N4O2S2/c1-4-15(23)22-18-19-11(3)16(26-18)13-10-25-17(21-13)20-12-8-6-7-9-14(12)24-5-2/h6-10H,4-5H2,1-3H3,(H,20,21)(H,19,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536342 (CHEMBL4548193) Show SMILES CN1C(NC(=O)\C=C\c2ccc(F)cc2)Sc2cc(ccc12)S(C)(=O)=O Show InChI InChI=1S/C18H17FN2O3S2/c1-21-15-9-8-14(26(2,23)24)11-16(15)25-18(21)20-17(22)10-5-12-3-6-13(19)7-4-12/h3-11,18H,1-2H3,(H,20,22)/b10-5+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536358 (CHEMBL2164269) Show SMILES Cc1nc(NC(=O)c2ccccc2)sc1-c1csc(Nc2ccc(cc2)S(N)(=O)=O)n1 Show InChI InChI=1S/C20H17N5O3S3/c1-12-17(30-20(22-12)25-18(26)13-5-3-2-4-6-13)16-11-29-19(24-16)23-14-7-9-15(10-8-14)31(21,27)28/h2-11H,1H3,(H,23,24)(H2,21,27,28)(H,22,25,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536348 (CHEMBL4545777) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(C)c2)n1 Show InChI InChI=1S/C16H16N4OS2/c1-9-5-4-6-12(7-9)19-15-20-13(8-22-15)14-10(2)17-16(23-14)18-11(3)21/h4-8H,1-3H3,(H,19,20)(H,17,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM50563891 (CHEMBL4793380) Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4NCCCOc34)cc2)no1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	903	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of recombinant human TAO2 (1 to 320 residues) using myelin basic protein as substrate incubated for 40 mins in presence of [gamma33P]ATP b...				Citation and Details Article DOI: 10.1016/j.ejmech.2017.09.018 BindingDB Entry DOI: 10.7270/Q270854P
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536344 (CHEMBL600947 | GNF-Pf-2911) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(Br)cc2)n1 Show InChI InChI=1S/C15H13BrN4OS2/c1-8-13(23-15(17-8)18-9(2)21)12-7-22-14(20-12)19-11-5-3-10(16)4-6-11/h3-7H,1-2H3,(H,19,20)(H,17,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536335 (CHEMBL4563650) Show SMILES O=C(NCC1COc2ccccc2O1)c1ccc2c(c1)[nH]c(=S)n(Cc1ccco1)c2=O Show InChI InChI=1S/C23H19N3O5S/c27-21(24-11-16-13-30-19-5-1-2-6-20(19)31-16)14-7-8-17-18(10-14)25-23(32)26(22(17)28)12-15-4-3-9-29-15/h1-10,16H,11-13H2,(H,24,27)(H,25,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536329 (CHEMBL1995377) Show SMILES Cc1cccc(NC(=S)N\N=C\c2c[nH]c3ccccc23)c1 Show InChI InChI=1S/C17H16N4S/c1-12-5-4-6-14(9-12)20-17(22)21-19-11-13-10-18-16-8-3-2-7-15(13)16/h2-11,18H,1H3,(H2,20,21,22)/b19-11+	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM42286 (5-[2-(2,5-dimethoxyanilino)-1,3-thiazol-4-yl]-4-me...) Show SMILES COc1ccc(OC)c(Nc2nc(cs2)-c2sc(N)nc2C)c1 Show InChI InChI=1S/C15H16N4O2S2/c1-8-13(23-14(16)17-8)11-7-22-15(19-11)18-10-6-9(20-2)4-5-12(10)21-3/h4-7H,1-3H3,(H2,16,17)(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536325 (CHEMBL4483432) Show SMILES COc1ccc(Cl)cc1Nc1nc(cs1)-c1sc(N)nc1C Show InChI InChI=1S/C14H13ClN4OS2/c1-7-12(22-13(16)17-7)10-6-21-14(19-10)18-9-5-8(15)3-4-11(9)20-2/h3-6H,1-2H3,(H2,16,17)(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536321 (CHEMBL1622765) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(O)c2)n1 Show InChI InChI=1S/C16H16N4O2S2/c1-3-13(22)20-16-17-9(2)14(24-16)12-8-23-15(19-12)18-10-5-4-6-11(21)7-10/h4-8,21H,3H2,1-2H3,(H,18,19)(H,17,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536320 (CHEMBL4590509) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(cc2)[N+]([O-])=O)n1 Show InChI InChI=1S/C16H15N5O3S2/c1-3-13(22)20-16-17-9(2)14(26-16)12-8-25-15(19-12)18-10-4-6-11(7-5-10)21(23)24/h4-8H,3H2,1-2H3,(H,18,19)(H,17,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536319 (CHEMBL4566039) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(c2)[N+]([O-])=O)n1 Show InChI InChI=1S/C16H15N5O3S2/c1-3-13(22)20-16-17-9(2)14(26-16)12-8-25-15(19-12)18-10-5-4-6-11(7-10)21(23)24/h4-8H,3H2,1-2H3,(H,18,19)(H,17,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536340 (CHEMBL4528019) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(cc2)S(N)(=O)=O)n1 Show InChI InChI=1S/C16H17N5O3S3/c1-3-13(22)21-16-18-9(2)14(26-16)12-8-25-15(20-12)19-10-4-6-11(7-5-10)27(17,23)24/h4-8H,3H2,1-2H3,(H,19,20)(H2,17,23,24)(H,18,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536311 (CHEMBL4593946) Show SMILES CN1C(NC(=O)c2ccc(cc2)C(=O)c2ccccc2)Sc2cc(ccc12)S(C)(=O)=O Show InChI InChI=1S/C23H20N2O4S2/c1-25-19-13-12-18(31(2,28)29)14-20(19)30-23(25)24-22(27)17-10-8-16(9-11-17)21(26)15-6-4-3-5-7-15/h3-14,23H,1-2H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536338 (CHEMBL4542920) Show SMILES Cc1nc(N)sc1-c1csc(Nc2ccc(cc2)[N+]([O-])=O)n1 Show InChI InChI=1S/C13H11N5O2S2/c1-7-11(22-12(14)15-7)10-6-21-13(17-10)16-8-2-4-9(5-3-8)18(19)20/h2-6H,1H3,(H2,14,15)(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536326 (CHEMBL4534844) Show SMILES COc1ccc(Cl)cc1Nc1nc(cs1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C16H15ClN4O2S2/c1-8-14(25-16(18-8)19-9(2)22)12-7-24-15(21-12)20-11-6-10(17)4-5-13(11)23-3/h4-7H,1-3H3,(H,20,21)(H,18,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536323 (CHEMBL4080220) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccccc2)n1 Show InChI InChI=1S/C15H14N4OS2/c1-9-13(22-15(16-9)17-10(2)20)12-8-21-14(19-12)18-11-6-4-3-5-7-11/h3-8H,1-2H3,(H,18,19)(H,16,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536322 (CHEMBL604514 | GNF-Pf-4167) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(C)cc2)n1 Show InChI InChI=1S/C16H16N4OS2/c1-9-4-6-12(7-5-9)19-15-20-13(8-22-15)14-10(2)17-16(23-14)18-11(3)21/h4-8H,1-3H3,(H,19,20)(H,17,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Homo sapiens (Human))	BDBM286984 (8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dich...) Show SMILES CNc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)c(=O)n(CCCN3CCN(CC3)C(=O)C=C)c2n1 |(-6.67,-.77,;-6.67,.77,;-5.33,1.54,;-5.33,3.08,;-4,3.85,;-2.67,3.08,;-1.33,3.85,;,3.08,;1.33,3.85,;1.33,5.39,;,6.16,;2.67,6.16,;2.67,7.7,;1.33,8.47,;4,5.39,;4,3.85,;5.33,3.08,;6.67,3.85,;2.67,3.08,;2.67,1.54,;,1.54,;1.33,.77,;-1.33,.77,;-1.33,-.77,;,-1.54,;,-3.08,;1.33,-3.85,;1.33,-5.39,;2.67,-6.16,;4,-5.39,;4,-3.85,;2.67,-3.08,;5.33,-6.16,;6.67,-5.39,;5.33,-7.7,;6.67,-8.47,;-2.67,1.54,;-4,.77,)| Show InChI InChI=1S/C26H30Cl2N6O4/c1-5-20(35)33-11-9-32(10-12-33)7-6-8-34-24-16(15-30-26(29-2)31-24)13-17(25(34)36)21-22(27)18(37-3)14-19(38-4)23(21)28/h5,13-15H,1,6-12H2,2-4H3,(H,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Principia Biopharma, Inc. Curated by ChEMBL					Assay Description Inhibition of human TAOK2 preincubated for 15 mins followed by peptide substrate addition measured after 3 hrs by caliper capillary electrophoresis m...				J Med Chem 60: 6516-6527 (2017) Article DOI: 10.1021/acs.jmedchem.7b00360 BindingDB Entry DOI: 10.7270/Q2C53P3H
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536324 (CHEMBL4072223) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(cc2)N(C)C)n1 Show InChI InChI=1S/C18H21N5OS2/c1-5-15(24)22-18-19-11(2)16(26-18)14-10-25-17(21-14)20-12-6-8-13(9-7-12)23(3)4/h6-10H,5H2,1-4H3,(H,20,21)(H,19,22,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536334 (CHEMBL3715362) Show SMILES CCOCCCn1c(=S)[nH]c2cc(ccc2c1=O)C(=O)NCC1COc2ccccc2O1 Show InChI InChI=1S/C23H25N3O5S/c1-2-29-11-5-10-26-22(28)17-9-8-15(12-18(17)25-23(26)32)21(27)24-13-16-14-30-19-6-3-4-7-20(19)31-16/h3-4,6-9,12,16H,2,5,10-11,13-14H2,1H3,(H,24,27)(H,25,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system using MBP as substrate measured after 30 mins in p...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50402265 (CHEMBL2164280 | US8802861, 1) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(c2)C(O)=O)n1 Show InChI InChI=1S/C16H14N4O3S2/c1-8-13(25-16(17-8)18-9(2)21)12-7-24-15(20-12)19-11-5-3-4-10(6-11)14(22)23/h3-7H,1-2H3,(H,19,20)(H,22,23)(H,17,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536334 (CHEMBL3715362) Show SMILES CCOCCCn1c(=S)[nH]c2cc(ccc2c1=O)C(=O)NCC1COc2ccccc2O1 Show InChI InChI=1S/C23H25N3O5S/c1-2-29-11-5-10-26-22(28)17-9-8-15(12-18(17)25-23(26)32)21(27)24-13-16-14-30-19-6-3-4-7-20(19)31-16/h3-4,6-9,12,16H,2,5,10-11,13-14H2,1H3,(H,24,27)(H,25,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536312 (CHEMBL1458296) Show SMILES CC(=O)c1cccc(Nc2nc(cs2)-c2sc(N)nc2C)c1 Show InChI InChI=1S/C15H14N4OS2/c1-8-13(22-14(16)17-8)12-7-21-15(19-12)18-11-5-3-4-10(6-11)9(2)20/h3-7H,1-2H3,(H2,16,17)(H,18,19)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536361 (CHEMBL1613587) Show SMILES Cc1nc(N)sc1-c1csc(Nc2cccc(O)c2)n1 Show InChI InChI=1S/C13H12N4OS2/c1-7-11(20-12(14)15-7)10-6-19-13(17-10)16-8-3-2-4-9(18)5-8/h2-6,18H,1H3,(H2,14,15)(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536352 (CHEMBL4561613) Show SMILES CN1C(NC(=O)CC2CCC(Br)CC2)Sc2cc(ccc12)S(C)(=O)=O |(19.7,-18.53,;20.86,-19.56,;20.7,-21.1,;19.36,-21.87,;18.02,-21.1,;18.02,-19.55,;16.69,-21.87,;16.69,-23.41,;15.36,-24.18,;15.35,-25.71,;16.68,-26.49,;16.68,-28.03,;18.02,-25.72,;18.03,-24.17,;22.11,-21.72,;23.14,-20.57,;24.68,-20.58,;25.46,-19.25,;24.68,-17.91,;23.14,-17.91,;22.38,-19.24,;27,-19.25,;27.76,-20.59,;27.39,-17.76,;28.49,-18.85,)| Show InChI InChI=1S/C17H23BrN2O3S2/c1-20-14-8-7-13(25(2,22)23)10-15(14)24-17(20)19-16(21)9-11-3-5-12(18)6-4-11/h7-8,10-12,17H,3-6,9H2,1-2H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536359 (CHEMBL4527282) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccccc2OC)n1 Show InChI InChI=1S/C17H18N4O2S2/c1-4-14(22)21-17-18-10(2)15(25-17)12-9-24-16(20-12)19-11-7-5-6-8-13(11)23-3/h5-9H,4H2,1-3H3,(H,19,20)(H,18,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536354 (CHEMBL1305300) Show SMILES Cc1nc(N)sc1-c1csc(Nc2ccc(cc2)S(N)(=O)=O)n1 Show InChI InChI=1S/C13H13N5O2S3/c1-7-11(22-12(14)16-7)10-6-21-13(18-10)17-8-2-4-9(5-3-8)23(15,19)20/h2-6H,1H3,(H2,14,16)(H,17,18)(H2,15,19,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536345 (CHEMBL4519027) Show SMILES CCOc1ccccc1Nc1nc(cs1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C17H18N4O2S2/c1-4-23-14-8-6-5-7-12(14)20-16-21-13(9-24-16)15-10(2)18-17(25-15)19-11(3)22/h5-9H,4H2,1-3H3,(H,20,21)(H,18,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536314 (CHEMBL4543595) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(O)cc2)n1 Show InChI InChI=1S/C16H16N4O2S2/c1-3-13(22)20-16-17-9(2)14(24-16)12-8-23-15(19-12)18-10-4-6-11(21)7-5-10/h4-8,21H,3H2,1-2H3,(H,18,19)(H,17,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536356 (CHEMBL4591485) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cc(Cl)ccc2C)n1 Show InChI InChI=1S/C17H17ClN4OS2/c1-4-14(23)22-17-19-10(3)15(25-17)13-8-24-16(21-13)20-12-7-11(18)6-5-9(12)2/h5-8H,4H2,1-3H3,(H,20,21)(H,19,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536357 (CHEMBL4553536) Show SMILES CCN(CC)c1ccc(Nc2nc(cs2)-c2sc(NC(C)=O)nc2C)cc1 Show InChI InChI=1S/C19H23N5OS2/c1-5-24(6-2)15-9-7-14(8-10-15)22-18-23-16(11-26-18)17-12(3)20-19(27-17)21-13(4)25/h7-11H,5-6H2,1-4H3,(H,22,23)(H,20,21,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536343 (CHEMBL4581349) Show SMILES Cc1nc(N)sc1-c1csc(Nc2cccc(c2)[N+]([O-])=O)n1 Show InChI InChI=1S/C13H11N5O2S2/c1-7-11(22-12(14)15-7)10-6-21-13(17-10)16-8-3-2-4-9(5-8)18(19)20/h2-6H,1H3,(H2,14,15)(H,16,17)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536318 (CHEMBL373492) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2cccc(c2)C(O)=O)n1 Show InChI InChI=1S/C17H16N4O3S2/c1-3-13(22)21-17-18-9(2)14(26-17)12-8-25-16(20-12)19-11-6-4-5-10(7-11)15(23)24/h4-8H,3H2,1-2H3,(H,19,20)(H,23,24)(H,18,21,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536341 (CHEMBL4520393) Show SMILES Cc1nc(N)sc1-c1csc(Nc2cccc(C)c2)n1 Show InChI InChI=1S/C14H14N4S2/c1-8-4-3-5-10(6-8)17-14-18-11(7-19-14)12-9(2)16-13(15)20-12/h3-7H,1-2H3,(H2,15,16)(H,17,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536336 (CHEMBL4536891) Show SMILES CN1C(NC(=O)CCCc2ccccc2)Sc2cc(ccc12)S(C)(=O)=O Show InChI InChI=1S/C19H22N2O3S2/c1-21-16-12-11-15(26(2,23)24)13-17(16)25-19(21)20-18(22)10-6-9-14-7-4-3-5-8-14/h3-5,7-8,11-13,19H,6,9-10H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536327 (CHEMBL4526718) Show SMILES CCc1ccccc1Nc1ncc(s1)-c1sc(NC(C)=O)nc1C Show InChI InChI=1S/C17H18N4OS2/c1-4-12-7-5-6-8-13(12)21-16-18-9-14(23-16)15-10(2)19-17(24-15)20-11(3)22/h5-9H,4H2,1-3H3,(H,18,21)(H,19,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536355 (CHEMBL4569913) Show SMILES CC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccccc2C)n1 Show InChI InChI=1S/C16H16N4OS2/c1-9-6-4-5-7-12(9)19-15-20-13(8-22-15)14-10(2)17-16(23-14)18-11(3)21/h4-8H,1-3H3,(H,19,20)(H,17,18,21)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536346 (CHEMBL4544171) Show SMILES CN1C(NC(=O)CCCOC2CCCCC2)Sc2cc(ccc12)S(C)(=O)=O Show InChI InChI=1S/C19H28N2O4S2/c1-21-16-11-10-15(27(2,23)24)13-17(16)26-19(21)20-18(22)9-6-12-25-14-7-4-3-5-8-14/h10-11,13-14,19H,3-9,12H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase TAO2 (Rattus norvegicus)	BDBM50536339 (CHEMBL4532396) Show SMILES CCC(=O)Nc1nc(C)c(s1)-c1csc(Nc2ccc(NC(C)=O)cc2)n1 Show InChI InChI=1S/C18H19N5O2S2/c1-4-15(25)23-18-19-10(2)16(27-18)14-9-26-17(22-14)21-13-7-5-12(6-8-13)20-11(3)24/h5-9H,4H2,1-3H3,(H,20,24)(H,21,22)(H,19,23,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Texas Southwestern Medical Center Curated by ChEMBL					Assay Description Inhibition of rat TAOK2 (1 to 320 residues) expressed in Baculovirus/insect cell expression system assessed as remaining activity using MBP as substr...				Bioorg Med Chem Lett 26: 3923-7 (2016) Article DOI: 10.1016/j.bmcl.2016.07.016 BindingDB Entry DOI: 10.7270/Q2G44TS3
					More data for this Ligand-Target Pair

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