BDBM50537652 CHEMBL4640293

SMILES: Cc1nn(-c2ccccc2)c2ncc(cc12)C(=O)c1cc(F)ccc1O

InChI Key: InChIKey=SIOCZFQDFPVIAQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50537652   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sepiapterin reductase (SPR) (Homo sapiens (Human))	BDBM50537652 (CHEMBL4640293) Show SMILES Cc1nn(-c2ccccc2)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C20H14FN3O2/c1-12-16-9-13(19(26)17-10-14(21)7-8-18(17)25)11-22-20(16)24(23-12)15-5-3-2-4-6-15/h2-11,25H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1007/s00044-008-9094-3 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair