Compile Data Set for Download or QSAR

Found 141 hits Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sepiapterin reductase (Homo sapiens (Human))	BDBM187257 (US9169234, 22) Show SMILES COCC(=O)NCCc1c(C)n(C)c2ccc(O)cc12 Show InChI InChI=1S/C15H20N2O3/c1-10-12(6-7-16-15(19)9-20-3)13-8-11(18)4-5-14(13)17(10)2/h4-5,8,18H,6-7,9H2,1-3H3,(H,16,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187258 (US9169234, 23) Show SMILES COCC(=O)NCCc1c(C)[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O3/c1-9-11(5-6-15-14(18)8-19-2)12-7-10(17)3-4-13(12)16-9/h3-4,7,16-17H,5-6,8H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sepiapterin reductase (Homo sapiens (Human))	BDBM187258 (US9169234, 23) Show SMILES COCC(=O)NCCc1c(C)[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O3/c1-9-11(5-6-15-14(18)8-19-2)12-7-10(17)3-4-13(12)16-9/h3-4,7,16-17H,5-6,8H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sepiapterin reductase (Homo sapiens (Human))	BDBM187257 (US9169234, 22) Show SMILES COCC(=O)NCCc1c(C)n(C)c2ccc(O)cc12 Show InChI InChI=1S/C15H20N2O3/c1-10-12(6-7-16-15(19)9-20-3)13-8-11(18)4-5-14(13)17(10)2/h4-5,8,18H,6-7,9H2,1-3H3,(H,16,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537670 (CHEMBL4641380) Show SMILES Cc1nn(C2CCCS2(=O)=O)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C18H16FN3O4S/c1-10-13-7-11(17(24)14-8-12(19)4-5-15(14)23)9-20-18(13)22(21-10)16-3-2-6-27(16,25)26/h4-5,7-9,16,23H,2-3,6H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Tested for inhibition of cGMP-dependent protein kinase from bovine lung				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537669 (CHEMBL4643608) Show SMILES Cc1nn(C2CCOCC2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C19H19N3O3/c1-12-16-10-13(18(24)15-4-2-3-5-17(15)23)11-20-19(16)22(21-12)14-6-8-25-9-7-14/h2-5,10-11,14,23H,6-9H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537671 (CHEMBL4633843) Show SMILES Cc1nn(C2CCOC2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C18H17N3O3/c1-11-15-8-12(17(23)14-4-2-3-5-16(14)22)9-19-18(15)21(20-11)13-6-7-24-10-13/h2-5,8-9,13,22H,6-7,10H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Tested for inhibition of cGMP-dependent protein kinase from bovine lung				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515168 (CHEMBL4469291) Show SMILES Oc1cc(F)cc(F)c1S(=O)(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C13H15F2NO3S/c14-9-6-10(15)12(11(17)7-9)20(18,19)16-5-4-13(8-16)2-1-3-13/h6-7,17H,1-5,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515126 (CHEMBL4451547) Show SMILES Oc1cc(F)ccc1S(=O)(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C13H16FNO3S/c14-10-2-3-12(11(16)8-10)19(17,18)15-7-6-13(9-15)4-1-5-13/h2-3,8,16H,1,4-7,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537661 (CHEMBL4648946) Show SMILES Cc1nn(-c2ccccn2)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C19H13FN4O2/c1-11-14-8-12(18(26)15-9-13(20)5-6-16(15)25)10-22-19(14)24(23-11)17-4-2-3-7-21-17/h2-10,25H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537648 (CHEMBL4640596) Show SMILES Cc1nn(CCO)c2ncc(cc12)C(=O)c1cc(Cl)ccc1O Show InChI InChI=1S/C16H14ClN3O3/c1-9-12-6-10(8-18-16(12)20(19-9)4-5-21)15(23)13-7-11(17)2-3-14(13)22/h2-3,6-8,21-22H,4-5H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537646 (CHEMBL512270) Show SMILES Cc1nn(C)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C15H12FN3O2/c1-8-11-5-9(7-17-15(11)19(2)18-8)14(21)12-6-10(16)3-4-13(12)20/h3-7,20H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537643 (CHEMBL1506565) Show SMILES Cc1n[nH]c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C14H10FN3O2/c1-7-10-4-8(6-16-14(10)18-17-7)13(20)11-5-9(15)2-3-12(11)19/h2-6,19H,1H3,(H,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537649 (CHEMBL1723285) Show SMILES Cc1nn(CCO)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C16H14FN3O3/c1-9-12-6-10(8-18-16(12)20(19-9)4-5-21)15(23)13-7-11(17)2-3-14(13)22/h2-3,6-8,21-22H,4-5H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537662 (CHEMBL4647748) Show SMILES Cc1nn(-c2cc(C)ccn2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C20H16N4O2/c1-12-7-8-21-18(9-12)24-20-16(13(2)23-24)10-14(11-22-20)19(26)15-5-3-4-6-17(15)25/h3-11,25H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537665 (CHEMBL4648066) Show SMILES Cc1nn(-c2ccccc2F)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C20H14FN3O2/c1-12-15-10-13(19(26)14-6-2-5-9-18(14)25)11-22-20(15)24(23-12)17-8-4-3-7-16(17)21/h2-11,25H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515137 (CHEMBL4476837) Show SMILES Oc1cc(F)cc(F)c1C(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C14H15F2NO2/c15-9-6-10(16)12(11(18)7-9)13(19)17-5-4-14(8-17)2-1-3-14/h6-7,18H,1-5,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537629 (CHEMBL4635339) Show SMILES CCn1ncc(C(=O)c2cc(Cl)c(cc2OC)N(C)S(=O)(=O)N(C)C)c1O Show InChI InChI=1S/C16H21ClN4O5S/c1-6-21-16(23)11(9-18-21)15(22)10-7-12(17)13(8-14(10)26-5)20(4)27(24,25)19(2)3/h7-9,23H,6H2,1-5H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187260 (US9169234, 32) Show SMILES COCC(=O)NCCc1cccc(O)c1 Show InChI InChI=1S/C11H15NO3/c1-15-8-11(14)12-6-5-9-3-2-4-10(13)7-9/h2-4,7,13H,5-6,8H2,1H3,(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537628 (CHEMBL4643853) Show SMILES Cc1nn(-c2ccccn2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C19H14N4O2/c1-12-15-10-13(18(25)14-6-2-3-7-16(14)24)11-21-19(15)23(22-12)17-8-4-5-9-20-17/h2-11,24H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537628 (CHEMBL4643853) Show SMILES Cc1nn(-c2ccccn2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C19H14N4O2/c1-12-15-10-13(18(25)14-6-2-3-7-16(14)24)11-21-19(15)23(22-12)17-8-4-5-9-20-17/h2-11,24H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	66.1	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Tested for inhibition of cGMP-dependent protein kinase from bovine lung				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sepiapterin reductase (Homo sapiens (Human))	BDBM187260 (US9169234, 32) Show SMILES COCC(=O)NCCc1cccc(O)c1 Show InChI InChI=1S/C11H15NO3/c1-15-8-11(14)12-6-5-9-3-2-4-10(13)7-9/h2-4,7,13H,5-6,8H2,1H3,(H,12,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	69	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537647 (CHEMBL1403506) Show SMILES Cc1nn(C)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C15H13N3O2/c1-9-12-7-10(8-16-15(12)18(2)17-9)14(20)11-5-3-4-6-13(11)19/h3-8,19H,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537659 (CHEMBL4646298) Show SMILES Cc1nn(-c2ccccn2)c2ncc(cc12)C(=O)c1cc(Cl)ccc1O Show InChI InChI=1S/C19H13ClN4O2/c1-11-14-8-12(18(26)15-9-13(20)5-6-16(15)25)10-22-19(14)24(23-11)17-4-2-3-7-21-17/h2-10,25H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515142 (CHEMBL4460134) Show SMILES Oc1cc(Cl)cc(Cl)c1S(=O)(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C13H15Cl2NO3S/c14-9-6-10(15)12(11(17)7-9)20(18,19)16-5-4-13(8-16)2-1-3-13/h6-7,17H,1-5,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187256 (US9169234, 21) Show SMILES COCC(=O)NCCc1cn(C)c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O3/c1-16-8-10(5-6-15-14(18)9-19-2)12-7-11(17)3-4-13(12)16/h3-4,7-8,17H,5-6,9H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	84	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187256 (US9169234, 21) Show SMILES COCC(=O)NCCc1cn(C)c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O3/c1-16-8-10(5-6-15-14(18)9-19-2)12-7-11(17)3-4-13(12)16/h3-4,7-8,17H,5-6,9H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515156 (CHEMBL4542798) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCc2ccccc12 Show InChI InChI=1S/C15H11Cl2NO2/c16-10-7-11(17)14(13(19)8-10)15(20)18-6-5-9-3-1-2-4-12(9)18/h1-4,7-8,19H,5-6H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537668 (CHEMBL4647815) Show SMILES Cc1nn(-c2ccncn2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C18H13N5O2/c1-11-14-8-12(17(25)13-4-2-3-5-15(13)24)9-20-18(14)23(22-11)16-6-7-19-10-21-16/h2-10,24H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537667 (CHEMBL4639207) Show SMILES Cc1nn(-c2ncccn2)c2ncc(cc12)C(=O)c1ccccc1O Show InChI InChI=1S/C18H13N5O2/c1-11-14-9-12(16(25)13-5-2-3-6-15(13)24)10-21-17(14)23(22-11)18-19-7-4-8-20-18/h2-10,24H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537652 (CHEMBL4640293) Show SMILES Cc1nn(-c2ccccc2)c2ncc(cc12)C(=O)c1cc(F)ccc1O Show InChI InChI=1S/C20H14FN3O2/c1-12-16-9-13(19(26)17-10-14(21)7-8-18(17)25)11-22-20(16)24(23-12)15-5-3-2-4-6-15/h2-11,25H,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Antagonist activity at CB1 receptor by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515170 (CHEMBL4483803) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCc2ccccc2C1 Show InChI InChI=1S/C16H13Cl2NO2/c17-12-7-13(18)15(14(20)8-12)16(21)19-6-5-10-3-1-2-4-11(10)9-19/h1-4,7-8,20H,5-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515183 (CHEMBL4566276) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C18H17Cl2NO2/c19-14-10-15(20)17(16(22)11-14)18(23)21-8-6-13(7-9-21)12-4-2-1-3-5-12/h1-5,10-11,13,22H,6-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515153 (CHEMBL4444034) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCC(C1)Nc1ccccc1 Show InChI InChI=1S/C17H16Cl2N2O2/c18-11-8-14(19)16(15(22)9-11)17(23)21-7-6-13(10-21)20-12-4-2-1-3-5-12/h1-5,8-9,13,20,22H,6-7,10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515125 (CHEMBL4562659) Show SMILES Oc1cccc(F)c1C(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C14H16FNO2/c15-10-3-1-4-11(17)12(10)13(18)16-8-7-14(9-16)5-2-6-14/h1,3-4,17H,2,5-9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515123 (CHEMBL4448911) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCC(Cc2ccccc2)CC1 Show InChI InChI=1S/C19H19Cl2NO2/c20-15-11-16(21)18(17(23)12-15)19(24)22-8-6-14(7-9-22)10-13-4-2-1-3-5-13/h1-5,11-12,14,23H,6-10H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515161 (CHEMBL4467218) Show SMILES Oc1cc(Cl)cnc1C(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C13H15ClN2O2/c14-9-6-10(17)11(15-7-9)12(18)16-5-4-13(8-16)2-1-3-13/h6-7,17H,1-5,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187258 (US9169234, 23) Show SMILES COCC(=O)NCCc1c(C)[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O3/c1-9-11(5-6-15-14(18)8-19-2)12-7-10(17)3-4-13(12)16-9/h3-4,7,16-17H,5-6,8H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair				3D Structure (crystal)
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515154 (CHEMBL4448675) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCC(C1)Oc1cccnc1 Show InChI InChI=1S/C16H14Cl2N2O3/c17-10-6-13(18)15(14(21)7-10)16(22)20-5-3-12(9-20)23-11-2-1-4-19-8-11/h1-2,4,6-8,12,21H,3,5,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187259 (US9169234, 24) Show SMILES COCC(=O)NCC(=O)c1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C13H14N2O4/c1-19-7-13(18)15-6-12(17)10-5-14-11-3-2-8(16)4-9(10)11/h2-5,14,16H,6-7H2,1H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187259 (US9169234, 24) Show SMILES COCC(=O)NCC(=O)c1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C13H14N2O4/c1-19-7-13(18)15-6-12(17)10-5-14-11-3-2-8(16)4-9(10)11/h2-5,14,16H,6-7H2,1H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	310	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50537639 (CHEMBL4639296) Show SMILES CC1CC(=O)C(C(=O)c2cc(C)c3c(-c4nn(C)cc4CCS3(=O)=O)c2C)C(=O)C1 |(27.74,-4.11,;29.07,-4.89,;29.07,-6.43,;30.4,-7.21,;30.39,-8.75,;31.72,-6.44,;33.06,-7.21,;33.05,-8.75,;34.39,-6.44,;34.39,-4.9,;35.72,-4.13,;35.71,-2.59,;37.05,-4.9,;37.06,-6.45,;38.29,-7.4,;38.16,-8.95,;39.59,-9.56,;39.93,-11.06,;40.6,-8.39,;39.8,-7.05,;40.47,-5.64,;39.79,-4.24,;38.26,-3.91,;37.49,-2.57,;39.03,-2.57,;35.72,-7.21,;35.72,-8.75,;31.73,-4.9,;33.07,-4.13,;30.41,-4.13,)| Show InChI InChI=1S/C22H24N2O5S/c1-11-7-16(25)19(17(26)8-11)21(27)15-9-12(2)22-18(13(15)3)20-14(10-24(4)23-20)5-6-30(22,28)29/h9-11,19H,5-8H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibitory potency against isolated epidermal growth factor receptor (EGFR) from human A431 carcinoma cells				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.126793 BindingDB Entry DOI: 10.7270/Q2Z89G99
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187250 (US9169234, 1) Show SMILES CC(C)C(=O)NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O2/c1-9(2)14(18)15-6-5-10-8-16-13-4-3-11(17)7-12(10)13/h3-4,7-9,16-17H,5-6H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187251 (US9169234, 2) Show SMILES Oc1ccc2[nH]cc(CCNC(=O)C3CC3)c2c1 Show InChI InChI=1S/C14H16N2O2/c17-11-3-4-13-12(7-11)10(8-16-13)5-6-15-14(18)9-1-2-9/h3-4,7-9,16-17H,1-2,5-6H2,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	340	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515176 (CHEMBL4567010) Show SMILES Oc1cc(F)cnc1C(=O)N1CCC2(CCC2)C1 Show InChI InChI=1S/C13H15FN2O2/c14-9-6-10(17)11(15-7-9)12(18)16-5-4-13(8-16)2-1-3-13/h6-7,17H,1-5,8H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187251 (US9169234, 2) Show SMILES Oc1ccc2[nH]cc(CCNC(=O)C3CC3)c2c1 Show InChI InChI=1S/C14H16N2O2/c17-11-3-4-13-12(7-11)10(8-16-13)5-6-15-14(18)9-1-2-9/h3-4,7-9,16-17H,1-2,5-6H2,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515150 (CHEMBL4437646) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCC(C1)c1cccnc1 Show InChI InChI=1S/C16H14Cl2N2O2/c17-12-6-13(18)15(14(21)7-12)16(22)20-5-3-11(9-20)10-2-1-4-19-8-10/h1-2,4,6-8,11,21H,3,5,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515182 (CHEMBL4456501) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCC(CCc2ccccc2)C1 Show InChI InChI=1S/C19H19Cl2NO2/c20-15-10-16(21)18(17(23)11-15)19(24)22-9-8-14(12-22)7-6-13-4-2-1-3-5-13/h1-5,10-11,14,23H,6-9,12H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187250 (US9169234, 1) Show SMILES CC(C)C(=O)NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O2/c1-9(2)14(18)15-6-5-10-8-16-13-4-3-11(17)7-12(10)13/h3-4,7-9,16-17H,5-6H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM50515178 (CHEMBL4449470) Show SMILES Oc1cc(Cl)cc(Cl)c1C(=O)N1CCCC2(CCC2)C1 Show InChI InChI=1S/C15H17Cl2NO2/c16-10-7-11(17)13(12(19)8-10)14(20)18-6-2-5-15(9-18)3-1-4-15/h7-8,19H,1-6,9H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Gr�nenthal GmbH Curated by ChEMBL					Assay Description Inhibition of TNAS binding to human sepiapterin reductase by 19F-NMR spectra analysis				J Med Chem 62: 6391-6397 (2019) Article DOI: 10.1021/acs.jmedchem.9b00218 BindingDB Entry DOI: 10.7270/Q2JW8J6W
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 141 total )  |  Next  |  Last  >>

Jump to: