Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Sepiapterin reductase' and Ligand = 'BDBM187250'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sepiapterin reductase (Homo sapiens (Human))	BDBM187250 (US9169234, 1) Show SMILES CC(C)C(=O)NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O2/c1-9(2)14(18)15-6-5-10-8-16-13-4-3-11(17)7-12(10)13/h3-4,7-9,16-17H,5-6H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	330	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the product ...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair
Sepiapterin reductase (Homo sapiens (Human))	BDBM187250 (US9169234, 1) Show SMILES CC(C)C(=O)NCCc1c[nH]c2ccc(O)cc12 Show InChI InChI=1S/C14H18N2O2/c1-9(2)14(18)15-6-5-10-8-16-13-4-3-11(17)7-12(10)13/h3-4,7-9,16-17H,5-6H2,1-2H3,(H,15,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	400	n/a	n/a	n/a	n/a	6.5	37
Children's Medical Center Corporation US Patent					Assay Description To screen for SPR inhibition, a biochemical assay based on LC/MS (and chromogenic) read-out has been developed. The LC/MS assay monitors the produc...				US Patent US9169234 (2015) BindingDB Entry DOI: 10.7270/Q20Z7233
					More data for this Ligand-Target Pair