null
SMILES: OC(=O)C(=O)Nc1ccc2nc(NC(=O)c3cc(Br)c(Br)[nH]3)[nH]c2c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA gyrase subunit A/B (Escherichia coli (strain K12)) | BDBM50547853![]() (CHEMBL4763407) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Escherichia coli DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 4 subunit A/B (Staphylococcus aureus) | BDBM50547853![]() (CHEMBL4763407) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA gyrase subunit A/B (Staphylococcus aureus) | BDBM50547853![]() (CHEMBL4763407) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Staphylococcus aureus DNA gyrase using relaxed pNO1 plasmid DNA as substrate incubated for 30 mins by fluorescence assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.0c00416 BindingDB Entry DOI: 10.7270/Q2JW8JGG | |||||||||||
More data for this Ligand-Target Pair |