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Enter Data

null

SMILES: OC1CCN(C1)C(=O)CCN1CCCc2ccccc12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50548777
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50548777 (CHEMBL4752380) Show SMILES OC1CCN(C1)C(=O)CCN1CCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.66E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M2 receptor (unknown origin) expressed in CHO-K1 cell membranes assessed as inhibition constant by radioliga...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127632 BindingDB Entry DOI: 10.7270/Q2862M3Q
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50548777 (CHEMBL4752380) Show SMILES OC1CCN(C1)C(=O)CCN1CCCc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M4 receptor (unknown origin) expressed in CHO-K1 cell membranes assessed as inhibition constant by radioliga...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127632 BindingDB Entry DOI: 10.7270/Q2862M3Q
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50548777 (CHEMBL4752380) Show SMILES OC1CCN(C1)C(=O)CCN1CCCc2ccccc12 Show InChI	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.13E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M1 receptor (unknown origin) expressed in CHO-K1 cell membranes assessed as inhibition constant by radioliga...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127632 BindingDB Entry DOI: 10.7270/Q2862M3Q
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50548777 (CHEMBL4752380) Show SMILES OC1CCN(C1)C(=O)CCN1CCCc2ccccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]-NMS from muscarinic M3 receptor (unknown origin) expressed in CHO-K1 cell membranes assessed as inhibition constant by radioliga...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127632 BindingDB Entry DOI: 10.7270/Q2862M3Q
TBA					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50548777 (CHEMBL4752380) Show SMILES OC1CCN(C1)C(=O)CCN1CCCc2ccccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.08E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human muscarinic M2 receptor expressed in CHO cells co-expressing Galpha15 assessed as inhibition of acetylcholine-induced cal...				Citation and Details Article DOI: 10.1016/j.bmcl.2020.127632 BindingDB Entry DOI: 10.7270/Q2862M3Q
TBA					More data for this Ligand-Target Pair