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SMILES: O=C1NCCC11CCN(CC1)c1c(cnc2[nH]ccc12)-c1ccc2ncsc2c1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50573477   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human))	BDBM50573477 (CHEMBL4868667) Show SMILES O=C1NCCC11CCN(CC1)c1c(cnc2[nH]ccc12)-c1ccc2ncsc2c1 Show InChI	PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of tracer 236 binding to recombinant human GST/His-tagged CDK11 (1 to 502 residues)/Cyclin C( 1 to 283 residues) expressed in insect cells...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00300 BindingDB Entry DOI: 10.7270/Q29W0K80
					More data for this Ligand-Target Pair
Cyclin-C (Homo sapiens (Human))	BDBM50573477 (CHEMBL4868667) Show SMILES O=C1NCCC11CCN(CC1)c1c(cnc2[nH]ccc12)-c1ccc2ncsc2c1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of tracer 236 binding to recombinant human His-tagged full length CDK8/Cyclin C expressed in baculovirus expression system by Lanthascreen...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00300 BindingDB Entry DOI: 10.7270/Q29W0K80
					More data for this Ligand-Target Pair