null
SMILES: O=C1NCCC11CCN(CC1)c1c(cnc2[nH]ccc12)-c1ccc2ncnn2c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-C/Cyclin-dependent kinase 19 (Homo sapiens (Human)) | BDBM50573479 (CHEMBL4854223) | PDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of tracer 236 binding to recombinant human GST/His-tagged CDK11 (1 to 502 residues)/Cyclin C( 1 to 283 residues) expressed in insect cells... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00300 BindingDB Entry DOI: 10.7270/Q29W0K80 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-C (Homo sapiens (Human)) | BDBM50573479 (CHEMBL4854223) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 274 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of tracer 236 binding to recombinant human His-tagged full length CDK8/Cyclin C expressed in baculovirus expression system by Lanthascreen... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00300 BindingDB Entry DOI: 10.7270/Q29W0K80 | |||||||||||
More data for this Ligand-Target Pair |