null
SMILES: COc1cncc2O[C@]3([C@@H]([C@@H](CO)[C@H](CN4CCOCC4)[C@@]3(O)c12)c1ccccc1)c1ccc(Br)cc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Eukaryotic initiation factor 4A-I (Homo sapiens (Human)) | BDBM50576673 (CHEMBL4849769) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring short 5'-UTR of tubulin | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128111 BindingDB Entry DOI: 10.7270/Q2GQ72K9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eukaryotic initiation factor 4A-I (Homo sapiens (Human)) | BDBM50576673 (CHEMBL4849769) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring highly structured 5'-UTR of c-Myc | Citation and Details Article DOI: 10.1016/j.bmcl.2021.128111 BindingDB Entry DOI: 10.7270/Q2GQ72K9 | |||||||||||
More data for this Ligand-Target Pair |