Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Eukaryotic initiation factor 4A-I' and Ligand = 'BDBM50576673'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50576673 (CHEMBL4849769) Show SMILES COc1cncc2O[C@]3([C@@H]([C@@H](CO)[C@H](CN4CCOCC4)[C@@]3(O)c12)c1ccccc1)c1ccc(Br)cc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring highly structured 5'-UTR of c-Myc				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128111 BindingDB Entry DOI: 10.7270/Q2GQ72K9
					More data for this Ligand-Target Pair
Eukaryotic initiation factor 4A-I (Homo sapiens (Human))	BDBM50576673 (CHEMBL4849769) Show SMILES COc1cncc2O[C@]3([C@@H]([C@@H](CO)[C@H](CN4CCOCC4)[C@@]3(O)c12)c1ccccc1)c1ccc(Br)cc1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of eIF4A (unknown origin) assessed as inhibition of translation of RNA featuring short 5'-UTR of tubulin				Citation and Details Article DOI: 10.1016/j.bmcl.2021.128111 BindingDB Entry DOI: 10.7270/Q2GQ72K9
					More data for this Ligand-Target Pair