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null

SMILES: [H][C@]12CN(C(C)=O)[C@]([H])(C[C@H]1c1ccc(cc1)-c1cc(cc3cc(ccc13)-c1ccc(cc1)C(F)(F)F)C(O)=O)C2

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50584884
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2B adrenergic receptor (Homo sapiens (Human))	BDBM50584884 (CHEMBL5075741) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of adrenergic alpha 2B receptor (unknown origin) assessed as binding constant				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470
TBA					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50584884 (CHEMBL5075741) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of dopamine D5 receptor (unknown origin) assessed as binding constant				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470
TBA					More data for this Ligand-Target Pair
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50584884 (CHEMBL5075741) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of sigma 2 receptor (unknown origin) assessed as binding constant				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470
TBA					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50584884 (CHEMBL5075741) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of sigma 1 receptor (unknown origin) assessed as binding constant				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470
TBA					More data for this Ligand-Target Pair
P2Y purinoceptor 14 (Homo sapiens (Human))	BDBM50584884 (CHEMBL5075741) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470
TBA					More data for this Ligand-Target Pair
P2Y purinoceptor 14 (Homo sapiens (Human))	BDBM50584884 (CHEMBL5075741) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of fluorescent antagonist binding to human P2Y14R expressed in CHO cells preincubated for 30 mins followed by 6-amino-9-(2-carboxy-4-((6-(...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01964 BindingDB Entry DOI: 10.7270/Q2611470
TBA					More data for this Ligand-Target Pair