null
SMILES: CC(C)(OCc1cc(-c2cccc(OC3CCC3)c2)n(n1)-c1cccc(c1)N1CCCC1)C(O)=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Monocarboxylate transporter 1 (Homo sapiens (Human)) | BDBM546730 (2-([5-(3-Cyclobutoxyphenyl)-1-[[2- (pyrrolidin-1-y...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... | Citation and Details BindingDB Entry DOI: 10.7270/Q2862KNG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monocarboxylate transporter 4 (Homo sapiens (Human)) | BDBM546730 (2-([5-(3-Cyclobutoxyphenyl)-1-[[2- (pyrrolidin-1-y...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... | Citation and Details BindingDB Entry DOI: 10.7270/Q2862KNG | |||||||||||
More data for this Ligand-Target Pair |