BDBM58065 (4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-pyrimidin-4-yl]hydrazinyl]methylidene]-2-ethoxy-cyclohexa-2,5-dien-1-one::(4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]hydrazinyl]methylidene]-2-ethoxycyclohexa-2,5-dien-1-one::(4E)-4-[[N'-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-pyrimidin-4-yl]hydrazino]methylene]-2-ethoxy-cyclohexa-2,5-dien-1-one::(4E)-4-[[[2-(3,5-dimethyl-1-pyrazolyl)-6-methyl-4-pyrimidinyl]hydrazo]methylidene]-2-ethoxy-1-cyclohexa-2,5-dienone::4-{[2-(3,5-Dimethyl-pyrazol-1-yl)-6-methyl-pyrimidin-4-yl]-hydrazonomethyl}-2-ethoxy-phenol::MLS000777513::SMR000413907::cid_6525018

SMILES: CCOc1cc(CN=Nc2cc(C)nc(n2)-n2nc(C)cc2C)ccc1O

InChI Key: InChIKey=ZIUDGXBHDIMSBO-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 58065   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
streptokinase A precursor (Streptococcus pyogenes M1 GAS)	BDBM58065 ((4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-...) Show SMILES CCOc1cc(CN=Nc2cc(C)nc(n2)-n2nc(C)cc2C)ccc1O |w:8.8| Show InChI InChI=1S/C19H22N6O2/c1-5-27-17-10-15(6-7-16(17)26)11-20-23-18-9-12(2)21-19(22-18)25-14(4)8-13(3)24-25/h6-10,26H,5,11H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2736PBV
					More data for this Ligand-Target Pair
Bcl-2-like protein 11 (Homo sapiens (Human))	BDBM58065 ((4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-...) Show SMILES CCOc1cc(CN=Nc2cc(C)nc(n2)-n2nc(C)cc2C)ccc1O |w:8.8| Show InChI InChI=1S/C19H22N6O2/c1-5-27-17-10-15(6-7-16(17)26)11-20-23-18-9-12(2)21-19(22-18)25-14(4)8-13(3)24-25/h6-10,26H,5,11H2,1-4H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	5.04E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM58065 ((4E)-4-[[2-[2-(3,5-dimethylpyrazol-1-yl)-6-methyl-...) Show SMILES CCOc1cc(CN=Nc2cc(C)nc(n2)-n2nc(C)cc2C)ccc1O |w:8.8| Show InChI InChI=1S/C19H22N6O2/c1-5-27-17-10-15(6-7-16(17)26)11-20-23-18-9-12(2)21-19(22-18)25-14(4)8-13(3)24-25/h6-10,26H,5,11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q20C4T6J
					More data for this Ligand-Target Pair