null
SMILES: COc1cc(Oc2ccc(F)cc2)ccc1CNC(=O)c1c(O)cc(O)cc1O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-directed RNA polymerase subunit beta' () | BDBM592146 (US11572337, Compound 0MTK178) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Escherichia coli: Fluorescence-detected RNA polymerase assays with E.coli RNA polymerase were performed by a modification of the procedure of Khulman... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA-directed RNA polymerase subunit beta (Escherichia coli) | BDBM592146 (US11572337, Compound 0MTK178) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 610 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Staphylococcus aureus: Fluorescence-detected RNA polymerase assays with S. aureus RNA polymerase were performed as in Example 2.1, using reaction mix... | Citation and Details BindingDB Entry DOI: 10.7270/Q2PZ5DR6 | |||||||||||
More data for this Ligand-Target Pair |