null
SMILES: Clc1cc2n(ncc2cc1C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N)-c1cccc(CC#N)n1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Ubiquitin carboxyl-terminal hydrolase 30 [57-517] (Homo sapiens (Human)) | BDBM592654![]() (6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou... | Citation and Details BindingDB Entry DOI: 10.7270/Q2NZ8CKC | |||||||||||
More data for this Ligand-Target Pair |