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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 30 [57-517]' and Ligand = 'BDBM592654'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase 30 [57-517]


(Homo sapiens (Human))
BDBM592654
PNG
(6-chloro-N-((1R,2R,4S)-7-cyano-7- azabicyclo[2.2.1...)
Show SMILES Clc1cc2n(ncc2cc1C(=O)N[C@@H]1C[C@@H]2CC[C@H]1N2C#N)-c1cccc(CC#N)n1 |r,THB:20:19:17.16:13.14|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/an/an/a


TBA

Assay Description
USP30 inhibition was tested with recombinant human USP30 using the fluorescent substrate Ubiquitin-Rhodamine 110 (UBPBio) in 1536-well format. Compou...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2NZ8CKC
More data for this
Ligand-Target Pair