null
SMILES: Fc1cnc(nc1Nc1ccc2[nH]ncc2c1)N1CCCNCC1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Rho-associated protein kinase 1 [1-535] (Homo sapiens (Human)) | BDBM598547 (N-(2-(1,4-diazepan-1-yl)-5-fluoropyrimidin-4-yl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Rho-associated protein kinase 2 [1-552] (Homo sapiens (Human)) | BDBM598547 (N-(2-(1,4-diazepan-1-yl)-5-fluoropyrimidin-4-yl)-1...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Recombinant ROCK1 (amino acids 1-535) and ROCK2 (amino acids 1-552) proteins were purchased from ThermoFisher Scientific. Compound's activities w... | Citation and Details BindingDB Entry DOI: 10.7270/Q2MP576K | |||||||||||
More data for this Ligand-Target Pair |